DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and hpn

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001091657.2	Gene:	hpn / 569259	ZFINID:	ZDB-GENE-141212-373	Length:	425	Species:	Danio rerio

Alignment Length:	262	Identity:	80/262 - (30%)
Similarity:	118/262 - (45%)	Gaps:	56/262 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 EPRIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHVITAGHC----VKHGNDVVPADLWSIQ 94
            |.|||||:.|:||.:|.|:||:..|.|.|||.|||...:|:|.||    .:|      |..|.:.
Zfish   161 EERIVGGVDARQGSWPWQVSLQYDGVHQCGGSIISDRWIISAAHCFPERYRH------ASRWRVL 219

  Fly    95 AGSLLLSSDGVRIPVAE---VIMHPNY-------ATGGHNDLAVLRLQSPL------------TF 137
            .||:..:.....:.:||   |:.|.:|       ......|:||:.|..||            |:
Zfish   220 MGSIYNTPIRKNVVIAEVKTVVYHSSYLPFVDANIDDNSRDIAVISLTKPLQFTDYIQPVCLPTY 284

  Fly   138 DANIAAIQLATEDPPNCVAVDISGWGNIAEKGPLSDSLLFVQVTSISRGACRWMFY--SRLPETM 200
            ...:|..|:.|          ::||||:...|..::.|....|..||...|....|  :::..||
Zfish   285 GQRLADGQMGT----------VTGWGNVEYYGTQANVLQEAHVPIISDAVCNGPDYYDNQVTTTM 339

  Fly   201 ICLLHSK-NSGACYGDSGGP--------ATYGGKVVGLASLLLGGGCGRAAPDG-YLRISKVRAW 255
            .|..:.| .:.:|.||||||        .|...:::|:.|  .|.||..|...| |.|:|:...|
Zfish   340 FCAGYEKGGTDSCQGDSGGPFVAADVLSKTSRYRLLGVVS--WGTGCAMAKKPGVYTRVSRFLPW 402

  Fly   256 IA 257
            |:
Zfish   403 IS 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	77/257 (30%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	63/210 (30%)
hpn	NP_001091657.2	SRCR_2	54..160	CDD:321960
hpn	NP_001091657.2	Tryp_SPc	164..404	CDD:238113	77/257 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910