DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and PRSS1

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_011514713.1	Gene:	PRSS1 / 5644	HGNCID:	9475	Length:	472	Species:	Homo sapiens

Alignment Length:	238	Identity:	72/238 - (30%)
Similarity:	109/238 - (45%)	Gaps:	34/238 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 EPRIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHVITAGHCVK---------HGNDVVPAD 89
            :.:||||...::...|:|:||. .|.|:|||.:|:...|::||||.|         |..:|:..:
Human   246 DDKIVGGYNCEENSVPYQVSLN-SGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGN 309

  Fly    90 LWSIQAGSLLLSSDGVRIPVAEVIMHPNYATGG-HNDLAVLRLQSPLTFDANIAAIQLATEDPPN 153
            ...|.|              |::|.||.|.... :||:.:::|.|....:|.::.|.|.|..|..
Human   310 EQFINA--------------AKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPAT 360

  Fly   154 CVAVDISGWGNIAEKG-PLSDSLLFVQVTSISRGACRWMFYSRLPETMIC---LLHSKNSGACYG 214
            .....||||||.|..| ...|.|..:....:|:..|...:..::...|.|   |...|:|  |.|
Human   361 GTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDS--CQG 423

  Fly   215 DSGGPATYGGKVVGLASLLLGGGCG-RAAPDGYLRISKVRAWI 256
            |||||....|::.|:.|  .|.||. :..|..|.::.....||
Human   424 DSGGPVVCNGQLQGVVS--WGDGCAQKNKPGVYTKVYNYVKWI 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	70/234 (30%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	60/195 (31%)
PRSS1	XP_011514713.1	Ig	19..119	CDD:299845
		IG_like	29..113	CDD:214653
		Tryp_SPc	248..464	CDD:214473	70/234 (30%)
		Tryp_SPc	249..467	CDD:238113	72/235 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBP0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820