DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and prss60.2

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	286	Identity:	87/286 - (30%)
Similarity:	136/286 - (47%)	Gaps:	46/286 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWTTLWTVLLLLLCGVQVILGQ-DVAQNQSESAIEPRIVGGIKAKQGQFPHQISLR--LRGEHYC 62
            ||......|.||:| |:..|.| :|.   .::.:..|||||:.|.:|.:|.|:||:  ..|.|:|
Zfish     1 MWRLTCATLTLLIC-VKGSLSQLNVC---GQAPLNSRIVGGVNAPEGSWPWQVSLQSPRYGGHFC 61

  Fly    63 GGVIISATHVITAGHCVKHGNDVVPADLWSIQAGSLLL-----SSDGVRI-----PVAEVIMHPN 117
            ||.:||:..|:||.||           |..:...||::     :..||..     .||::|:|.:
Zfish    62 GGSLISSEWVLTAAHC-----------LPGVSESSLVVYLGRRTQQGVNTHETSRNVAKIIVHSS 115

  Fly   118 Y-ATGGHNDLAVLRLQSPLTFDANIAAIQLATEDPPNCVAVD--ISGWG------NIAEKGPLSD 173
            | :....||:|:|||.|.:||:..|..:.||.::........  |:|||      |:...|.|.:
Zfish   116 YNSNTNDNDIALLRLSSAVTFNDYIRPVCLAAQNSVYSAGTSSWITGWGDVQAGVNLPAPGILQE 180

  Fly   174 SLLFVQVTSISRGACRWMFYS-RLPETMICL-LHSKNSGACYGDSGGPATYGGKVVGLASLLLGG 236
            :::.|    ::...|.....| .:...|||. |.......|.||||||.......|.:.:.:...
Zfish   181 TMIPV----VANDRCNAQLGSGTVTNNMICAGLAKGGKDTCQGDSGGPMVTRLCTVWIQAGITSW 241

  Fly   237 GCGRAAPDG---YLRISKVRAWIAEK 259
            |.|.|.|:.   |.|:|:.::||:.|
Zfish   242 GYGCADPNSPGVYTRVSQYQSWISSK 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	74/245 (30%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	63/204 (31%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	74/245 (30%)
		Tryp_SPc	34..267	CDD:238113	75/247 (30%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587855
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840