DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and prss27

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	277	Identity:	84/277 - (30%)
Similarity:	131/277 - (47%)	Gaps:	41/277 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VLLLLLCGVQVILGQDVAQNQSESAIEPRIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHV 72
            ::.|||.|..|..   ::....:.|...|||||..|..|::|.|:|:..:..|.|||.::|:..|
Frog   394 IISLLLAGFAVTA---ISTGCGQPAFSDRIVGGNNAVFGEWPWQVSIVYQNSHICGGSLVSSNWV 455

  Fly    73 ITAGHCVKHGNDVVPADLWSIQAGSLL--------LSSDGVRIPVAEVIMHPNY-ATGGHNDLAV 128
            ::|.||....        :.|:...:|        |:||.|.|.|..||.:|.| ..|...|:|:
Frog   456 VSAAHCFPRS--------YKIENMQVLLGCFALMNLTSDAVIIRVKRVITYPLYTGEGSSGDIAM 512

  Fly   129 LRLQSPLTFDANI--AAIQLATEDPPNCVAVDISGWGNIAEKGPLSD--SLLFVQVTSISRGACR 189
            :.::||:|:.:.|  ..|.|..||.|:.....::|||||.....||.  .|..|:|..::..:|.
Frog   513 VEMESPVTYSSYILPICIPLTNEDFPSGKMCWVTGWGNIQSDVSLSPPYPLQEVEVPLVNASSCD 577

  Fly   190 WMFY---------SRLPETMICLLHSK-NSGACYGDSGGP-ATYGGK---VVGLASLLLGGGCGR 240
            .|::         ..:.:.|||..:.: ...||.|||||| |...|.   :.|:.|  .|.||.:
Frog   578 TMYHYNSDLNPATQLVHDDMICAGYPEGQKDACQGDSGGPLACKSGNYWFLTGIVS--WGDGCAQ 640

  Fly   241 A-APDGYLRISKVRAWI 256
            . .|..|.::|...:||
Frog   641 PNRPGVYTKVSSFSSWI 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	76/247 (31%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	63/204 (31%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113	77/248 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910