DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and tmprss2

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001008623.1	Gene:	tmprss2 / 494080	ZFINID:	ZDB-GENE-041212-48	Length:	486	Species:	Danio rerio

Alignment Length:	279	Identity:	84/279 - (30%)
Similarity:	126/279 - (45%)	Gaps:	46/279 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GVQVILGQD---VAQNQSESAIE-----------PRIVGGIK-AKQGQFPHQISLRLRGEHYCGG 64
            |.|.||...   ::..||.:|:.           .|||||.. ..:|.:|.|:||...|.|.|||
Zfish   216 GYQGILSPSLDFISACQSSTAVSLKCTDCGRSTGNRIVGGTTVTSKGVWPWQVSLHYSGRHLCGG 280

  Fly    65 VIISATHVITAGHCVKHGNDVVPADLWSIQAGSL----LLSSDGVRIPVAEVIMHPNYATGGHND 125
            .||:...::||.|||...::  |.. |::.||.|    :.|:.|  ..|..:::|........||
Zfish   281 SIITPYWILTAAHCVHQFSN--PGG-WTVYAGYLTQSEMASASG--NSVNRIVIHDFNPNTNEND 340

  Fly   126 LAVLRLQSPLTFDANIAAIQLATEDPPNCVAVD--ISGWGNIAEKGPLSDSLLFVQVTSISRGAC 188
            :|::||.:.||...||..:.|..:........|  ::|||.:...|..|.:|...::..|....|
Zfish   341 IALMRLNTALTISTNIRPVCLPNKGMSFTAQQDCYVTGWGALFSGGSSSATLQEAKIQLIDSTIC 405

  Fly   189 --RWMFYSRLPETMICLLHSKNSG---ACYGDSGGPATYGGKVVGLASL--LL-----GGGCG-R 240
              |.::...:.:||||.  .|.:|   :|.||||||.     |..:.||  ||     |.||. |
Zfish   406 NSRPVYNGLITDTMICA--GKLAGGVDSCQGDSGGPL-----VTNVRSLWWLLGDTSWGDGCAVR 463

  Fly   241 AAPDGYLRISKVRAWIAEK 259
            ..|..|..::....||.::
Zfish   464 NKPGVYGNVTYFLDWIYQQ 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	75/239 (31%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	61/193 (32%)
tmprss2	NP_001008623.1	LDLa	132..168	CDD:238060
		SRCR_2	173..248	CDD:295335	7/31 (23%)
		Tryp_SPc	251..479	CDD:214473	75/239 (31%)
		Tryp_SPc	252..482	CDD:238113	76/241 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910