DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and ACR

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001088.2	Gene:	ACR / 49	HGNCID:	126	Length:	421	Species:	Homo sapiens

Alignment Length:	309	Identity:	87/309 - (28%)
Similarity:	129/309 - (41%)	Gaps:	84/309 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLLLCGVQVI----------LGQDVAQNQSESAIEPRIVGGIKAKQGQFPHQISLRL-----RGE 59
            :||:..|.|:          .|....||.....   |||||..|:.|.:|..:||::     ...
Human     9 ILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGV---RIVGGKAAQHGAWPWMVSLQIFTYNSHRY 70

  Fly    60 HYCGGVIISATHVITAGHCVKHGNDVVPADLWSIQAGSLLL---SSDGVRIPVAE-----VIMHP 116
            |.|||.::::..|:||.||....|:|..   |.:..|:..:   ::..|:.|:.|     :|:|.
Human    71 HTCGGSLLNSRWVLTAAHCFVGKNNVHD---WRLVFGAKEITYGNNKPVKAPLQERYVEKIIIHE 132

  Fly   117 NY--ATGGHNDLAVLRLQSPLTFDANIAAIQLATEDPPNCV------------AVDISGWGNIAE 167
            .|  ||.| ||:|::.:..|::....|.         |.|:            :..::|||.|.|
Human   133 KYNSATEG-NDIALVEITPPISCGRFIG---------PGCLPHFKAGLPRGSQSCWVAGWGYIEE 187

  Fly   168 KGPLSDSLLF-VQVTSISRGAC---RWMFYSRLPETMICLLHSKNS-GACYGDSGGP-------- 219
            |.|...|:|. .:|..|....|   :| :..|:..|.:|..:.... ..|.||||||
Human   188 KAPRPSSILMEARVDLIDLDLCNSTQW-YNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKE 251

  Fly   220 ATYGGKVVGLASLLLGGGCGRAAPDG-------YLRISKVRAWIAEKAG 261
            :.|  .|||:.|  .|.||.||...|       ||.      |||.|.|
Human   252 SAY--VVVGITS--WGVGCARAKRPGIYTATWPYLN------WIASKIG 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	75/266 (28%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	59/213 (28%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	75/266 (28%)
		Tryp_SPc	43..288	CDD:238113	77/268 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	397..421
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910