DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and AgaP_AGAP012502

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_001230484.2	Gene:	AgaP_AGAP012502 / 4578454	VectorBaseID:	AGAP012502	Length:	829	Species:	Anopheles gambiae

Alignment Length:	227	Identity:	71/227 - (31%)
Similarity:	97/227 - (42%)	Gaps:	45/227 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 CGGVIISATHVITAGHCVKHGNDVVPADLWSIQAGSLLLSSDGVRIPVAE-----VIMHPNYATG 121
            |||.:|.|..::||.||.|..:.::|.|:  |:.|.|.|..|.....|.|     ||.||.|.|.
Mosquito    46 CGGSLIWANFILTAAHCTKDRDTLLPPDI--IRIGDLNLYDDREDALVQERTIIRVIRHPLYNTS 108

  Fly   122 G-HNDLAVLRLQSPLTFDANIAAIQLATEDPPNCVAVDISGWG---------NIAEKGPLS---- 172
            . ..|:|:|.|...:.....:....|..:|......|:.:|||         ||..|..|.
Mosquito   109 SVFYDIALLMLNEKVNIYFEVMPTCLWLDDNIPFSKVEAAGWGTSGFGYGKTNILIKAELKLMAN 173

  Fly   173 ---DSLLFVQVTSISRGACRWMFYSRLPETMICLLHSKNSGACYGDSGGP----ATYGG-KV--- 226
               :| .:.||.|:..|         |.|..:| ...|....|.||||||    ..:|. ||
Mosquito   174 KDCES-YYSQVASVKNG---------LMEHQLC-AWDKVMDTCPGDSGGPLQHKLIFGDYKVPFL 227

  Fly   227 VGLASLLLGGGCGRAAPDGYLRISKVRAWIAE 258
            ||:.|  .|..||.:.|..|:::||..:||.|
Mosquito   228 VGVTS--FGLSCGNSQPGVYVKVSKFGSWIVE 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	68/223 (30%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	53/178 (30%)
AgaP_AGAP012502	XP_001230484.2	Tryp_SPc	19..258	CDD:238113	71/227 (31%)
		Tryp_SPc	19..255	CDD:214473	68/223 (30%)
		Tryp_SPc	325..>418	CDD:304450
		Trypsin	621..823	CDD:278516
		Tryp_SPc	629..826	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910