DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and Tmprss11b

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001004020.1	Gene:	Tmprss11b / 365265	RGDID:	1303278	Length:	420	Species:	Rattus norvegicus

Alignment Length:	254	Identity:	84/254 - (33%)
Similarity:	128/254 - (50%)	Gaps:	38/254 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SAIEPRIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHVITAGHCVKHGNDVVPADLWSIQA 95
            ||...||.||..|::|::|.|.|||:.|:|:||..:|....::||.||....|:  |.:
  Rat   183 SATYDRITGGSTAQKGEWPWQASLRVNGKHHCGASLIGERFLLTAAHCFLRTNN--PKN------ 239

  Fly    96 GSLLLSSDGVRIP-------VAEVIMHPNYATG-GHNDLAVLRLQSPLTF--DANIAAIQLATED 150
               |..|.|.|:.       |.|||:|.:|..| .|:|:|:::|...::|  |.:...:..||:.
  Rat   240 ---LTVSFGTRVTPAYMQHYVEEVIIHEDYVKGQHHDDVAIIKLTEKVSFRNDVHRVCLPEATQV 301

  Fly   151 PPNCVAVDISGWGNIAEKGPLSDSLLFVQVTS---ISRGAC--RWMFYSRLPETMICLLHSKN-S 209
            .|....|.::|||:::..|   .|.|.:|..|   |...||  ...:..|:.:||:|..:.:. .
  Rat   302 FPPGEGVVVTGWGSLSYNG---KSPLLLQKASIKIIDTNACNSEEAYGGRIMDTMLCAGYMEGYV 363

  Fly   210 GACYGDSGGPATYGGK-----VVGLASLLLGGGCGRA-APDGYLRISKVRAWIAEKAGL 262
            .||.||||||..:...     :||:.|  .|..|||. .|..|:|::..|.|||.|.|:
  Rat   364 DACQGDSGGPLVHPNSRDIWYLVGIVS--WGHECGRVNKPGVYMRVTSYRDWIASKTGI 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	77/241 (32%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	63/197 (32%)
Tmprss11b	NP_001004020.1	SEA	50..144	CDD:279699
		Tryp_SPc	188..414	CDD:214473	77/241 (32%)
		Tryp_SPc	189..417	CDD:238113	79/243 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910