Protein Alignment CG32523 and PRSS48

DIOPT Version :10

• Sequence 1: NP_728401.1
• Gene: CG32523 / 318071
• FlyBaseID: FBgn0052523
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_001340540.1
• Gene: PRSS48 / 345062
• HGNCID: 24635
• Length: 346
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 86/276 - (31%)
• Similarity: 127/276 - (46%)
• Gaps: 52/276 - (18%)

  Fly    10 LLLLCGVQVILGQDVAQNQSESAIEPRIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHVIT 74
            ||||.|:.| .||.|..:        |:|||..|..|::|.|:||.......|||.::|...::|
Human    10 LLLLLGISV-CGQPVYSS--------RVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILT 65

  Fly    75 AGHCVKHGNDVVPADLW--SIQAGSLLLSSDGVRIPVAEVIMHPNY--ATGGHNDLAVLRLQSPL 135
            |.||::.........:|  ||..|.   |...|:..|:::::||.|  .|.   |:|:|:|.|.:
Human    66 AAHCIQPTWTTFSYTVWLGSITVGD---SRKRVKYYVSKIVIHPKYQDTTA---DVALLKLSSQV 124

  Fly   136 TFDANIAAI-------QLATEDPPNCVAVDISGWGNIAEKGPLSD-----SLLFVQVTSISRGAC 188
            ||.:.|..|       |||.  ||.|.   ::|||.:.|.   ||     :|...:|..|.|.||
Human   125 TFTSAILPICLPSVTKQLAI--PPFCW---VTGWGKVKES---SDRDYHSALQEAEVPIIDRQAC 181

  Fly   189 RWMFYS---RLP-------ETMICLLHSKN-SGACYGDSGGPAT--YGGKVVGLASLLLGGGCGR 240
            ..::..   .||       |..||...::| ..:|.||||||.:  ..|..:....:..|..||:
Human   182 EQLYNPIGIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECGK 246

  Fly   241 AAPDGYLRISKVRAWI 256
            :.|..|..:...:.||
Human   247 SLPGVYTNVIYYQKWI 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	66/208 (32%)
PRSS48	NP_001340540.1	Tryp_SPc	28..265	CDD:238113	76/249 (31%)