DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and OVCH1

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_024304736.1	Gene:	OVCH1 / 341350	HGNCID:	23080	Length:	1120	Species:	Homo sapiens

Alignment Length:	272	Identity:	82/272 - (30%)
Similarity:	129/272 - (47%)	Gaps:	32/272 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 TVLLLL--LCGVQVILGQDVAQNQSESAIEPRIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISA 69
            ||..:|  :||:...         |...:..||.||.:|....:|.|:.||..|::.|||.||:.
Human   587 TVKAILHDVCGIPPF---------SPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINP 642

  Fly    70 THVITAGHCVKHGNDVVPADLWSIQAG----SLLLSSDGVRIPVAEVIMHPNYATGGH-NDLAVL 129
            ..::||.|||:..|:.:.   |:|.||    :|..|::.|| ....:|:|.::.|..: :|:|::
Human   643 VWILTAAHCVQLKNNPLS---WTIIAGDHDRNLKESTEQVR-RAKHIIVHEDFNTLSYDSDIALI 703

  Fly   130 RLQSPLTFDANIAAIQLATEDPP--NCVAVDISGWGNIAEKGPLSDSLLFVQVTSISRGACRWMF 192
            :|.|||.:::.:..:.|.....|  :.....::|||:|:..|.|:..|..:||..:.|..|...:
Human   704 QLSSPLEYNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTY 768

  Fly   193 YSRLP----ETMIC--LLHSKNSGACYGDSGGPAT---YGGKVVGLASLLLGGGCGRA-APDGYL 247
            ||..|    |.|||  ...|.....|.||||||..   ..|..|....:..|.||.:. .|..:.
Human   769 YSAHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFA 833

  Fly   248 RISKVRAWIAEK 259
            |:.....||..|
Human   834 RVMIFLDWIQSK 845

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	73/236 (31%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	63/194 (32%)
OVCH1	XP_024304736.1	Tryp_SPc	58..294	CDD:238113
		CUB	336..444	CDD:238001
		CUB	454..565	CDD:238001
		Tryp_SPc	610..845	CDD:238113	74/238 (31%)
		CUB	881..978	CDD:238001
		CUB	1017..1119	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910