DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and Prss53

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	241	Identity:	71/241 - (29%)
Similarity:	109/241 - (45%)	Gaps:	45/241 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 WTVLLLLLCGVQVILGQDVAQ----NQSESAIEPRIVGGIKAKQGQFPHQISLRLRGEHYCGGVI 66
            |...||::..|.||.|...||    .:.....||:....:   .|::|.|.|:|.:|.|.|.|.:
Mouse     5 WRPELLIVGAVVVIEGLQAAQRACGQRGPGPPEPQEGNTL---PGEWPWQASVRRQGVHICSGSL 66

  Fly    67 ISATHVITAGHCVKHGNDVVPADL--WSIQAGSLLLSSDGVRIPVAEVI---------MHPNYAT 120
            ::.|.|:||.||.:   .:..|:|  ||:..||  |..:| :.|.||.:         .:.:|:.
Mouse    67 VADTWVLTAAHCFE---KMATAELSSWSVVLGS--LKQEG-QSPGAEEVGVAALQLPKAYNHYSQ 125

  Fly   121 GGHNDLAVLRLQSPLTFDANIAAIQLATEDP--PNCVAVDISGWGNIAEKGPLSDSLLFVQVTSI 183
            |  :|||:|:|..| |....:...|.....|  .:|.|   :||..  ....:|.:|..:::..|
Mouse   126 G--SDLALLQLTHP-TVQTTLCLPQPTYHFPFGASCWA---TGWDQ--NTSDVSRTLRNLRLRLI 182

  Fly   184 SRGACRWMFYSRLPET---------MIC-LLHSKNSGACYGDSGGP 219
            ||..|..: |:||.:.         |:| .......|.|.||||||
Mouse   183 SRPTCNCL-YNRLHQRLLSNPARPGMLCGGAQPGEQGPCQGDSGGP 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	60/207 (29%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	58/204 (28%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46		2/21 (10%)
		Tryp_SPc	45..271	CDD:238113	60/198 (30%)
		Tryp_SPc	311..522	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100