DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and GZMM

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_005308.2	Gene:	GZMM / 3004	HGNCID:	4712	Length:	257	Species:	Homo sapiens

Alignment Length:	220	Identity:	66/220 - (30%)
Similarity:	94/220 - (42%)	Gaps:	33/220 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SAIEPRIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHVITAGHCVKHGNDVVPADLWSIQA 95
            |:...:|:||.:......|:..||:..|.|.||||::....|:||.||:...    .|.| .:..
Human    20 SSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQR----MAQL-RLVL 79

  Fly    96 GSLLLSSDGVRIPVAEVIMHPNY--ATGGHNDLAVLRLQS---------PLTFDANIAAIQLATE 149
            |...|.|.|:...:...|.||.|  .....||||:|:|..         ||...:....:...|
Human    80 GLHTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAAGT- 143

  Fly   150 DPPNCVAVDISGWGNIAEKGPLSDSLLFVQVTSISRGACR----WMFYSRLPETMICL-LHSKNS 209
               .|   .::|||...:.|.||..|..:.:..:....|.    |  ...|..:|:|| ..||:.
Human   144 ---RC---SMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFW--NGSLSPSMVCLAADSKDQ 200

  Fly   210 GACYGDSGGPATYG-GKVVGLASLL 233
            ..|.||||||...| |:|  ||.:|
Human   201 APCKGDSGGPLVCGKGRV--LARVL 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	65/215 (30%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	57/197 (29%)
GZMM	NP_005308.2	Tryp_SPc	26..252	CDD:238113	65/214 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910