DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and Tmprss11d

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_663536.1	Gene:	Tmprss11d / 231382	MGIID:	2385221	Length:	417	Species:	Mus musculus

Alignment Length:	243	Identity:	82/243 - (33%)
Similarity:	122/243 - (50%)	Gaps:	22/243 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 EPRIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHVITAGHCVK-HGNDVVPADLWSIQAGS 97
            |.||:||::|:.|.:|.|:||:|...|:|||.:||...|:||.||.| :.|    ...|:...|
Mouse   183 EERIIGGMQAEPGDWPWQVSLQLNNVHHCGGALISNMWVLTAAHCFKSYPN----PQYWTATFG- 242

  Fly    98 LLLSSDGVRIPVAEVIMHPNYAT-GGHNDLAVLRLQSPLTFDANIAAIQL--ATED-PPNCVAVD 158
            :...|..:|:.|..::.|..|:: ...||:||::|...:.|..||..:.|  ||:: .|..||.
Mouse   243 VSTMSPRLRVRVRAILAHDGYSSVTRDNDIAVVQLDRSVAFSRNIHRVCLPAATQNIIPGSVAY- 306

  Fly   159 ISGWGNIAEKGPLSDSLLFVQVTSISRGACRW-MFYSR--LPETMICLLHSKNSGACYGDSGGPA 220
            ::|||::...|....:|...:|..||...|.. ..||.  ||..:...:.|....||.||||||.
Mouse   307 VTGWGSLTYGGNAVTNLRQGEVRIISSEECNTPAGYSGSVLPGMLCAGMRSGAVDACQGDSGGPL 371

  Fly   221 TYGGK-----VVGLASLLLGGGCGRA-APDGYLRISKVRAWIAEKAGL 262
            .....     |||:.|  .|..||.. .|..|.|::..|.||.::.|:
Mouse   372 VQEDSRRLWFVVGIVS--WGYQCGLPNKPGVYTRVTAYRNWIRQQTGI 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	78/233 (33%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	64/189 (34%)
Tmprss11d	NP_663536.1	SEA	48..140	CDD:279699
		Tryp_SPc	185..411	CDD:214473	78/233 (33%)
		Tryp_SPc	186..414	CDD:238113	79/235 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910