DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and F11

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_005262878.1	Gene:	F11 / 2160	HGNCID:	3529	Length:	626	Species:	Homo sapiens

Alignment Length:	258	Identity:	68/258 - (26%)
Similarity:	120/258 - (46%)	Gaps:	39/258 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 NQSESAIEPRIVGGIKAKQGQFPHQISLRLRG---EHYCGGVIISATHVITAGHCVKHGNDVVPA 88
            |:..:.|:||||||..:.:|::|.|::|....   .|.|||.||....::||.||
Human   379 NECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHC---------- 433

  Fly    89 DLWSIQAGSLL-----------LSSDGVRIPVAEVIMHPNY--ATGGHNDLAVLRLQSPLTFDAN 140
             .:.:::..:|           :..|.....|.|:|:|..|  |..|: |:|:|:|::.:.:..:
Human   434 -FYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGY-DIALLKLETTVNYTDS 496

  Fly   141 IAAIQLATEDPPNCVAVD--ISGWGNIAEKGPLSDSLLFVQVTSISRGACRWMFYS-RLPETMIC 202
            ...|.|.::...|.:..|  ::|||....:..:.::|...::..::...|:..:.. ::...|||
Human   497 QRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMIC 561

  Fly   203 LLHSK-NSGACYGDSGGPATYGGK----VVGLASLLLGGGCG-RAAPDGYLRISKVRAWIAEK 259
            ..:.: ...||.||||||.:....    :||:.|  .|.||. |..|..|..:.:...||.||
Human   562 AGYREGGKDACKGDSGGPLSCKHNEVWHLVGITS--WGEGCAQRERPGVYTNVVEYVDWILEK 622

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	61/244 (25%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	49/201 (24%)
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519
		Tryp_SPc	388..619	CDD:214473	61/244 (25%)
		Tryp_SPc	389..619	CDD:238113	60/243 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910