DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32523 and F9

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_000124.1	Gene:	F9 / 2158	HGNCID:	3551	Length:	461	Species:	Homo sapiens

Alignment Length:	247	Identity:	74/247 - (29%)
Similarity:	117/247 - (47%)	Gaps:	32/247 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHVITAGHCVKHGNDVVPADLWSIQAGSLLL 100
            |:|||..||.||||.|:.|..:.:.:|||.|::...::||.|||:.|..:      ::.||...:
Human   226 RVVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKI------TVVAGEHNI 284

  Fly   101 SS---DGVRIPVAEVIMHPNY--ATGGHN-DLAVLRLQSPLTFDANIAAIQLATEDPPNCV---- 155
            ..   ...:..|..:|.|.||  |...:| |:|:|.|..||..::.:..|.:|.::..|..
Human   285 EETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFG 349

  Fly   156 AVDISGWGNIAEKGPLSDSLLFVQVTSISRGAC----RWMFYSRLPETMICL-LHSKNSGACYGD 215
            :..:||||.:..||..:..|.:::|..:.|..|    ::..|:    .|.|. .|.....:|.||
Human   350 SGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYN----NMFCAGFHEGGRDSCQGD 410

  Fly   216 SGGPATYGGKVVGLASLL----LGGGCGRAAPDG-YLRISKVRAWIAEKAGL 262
            ||||  :..:|.|.:.|.    .|..|......| |.::|:...||.||..|
Human   411 SGGP--HVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKL 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	69/239 (29%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	58/196 (30%)
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:317114
		Tryp_SPc	227..457	CDD:238113	70/241 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910