DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_663378.1	Gene:	Tmprss4 / 214523	MGIID:	2384877	Length:	435	Species:	Mus musculus

Alignment Length:	259	Identity:	83/259 - (32%)
Similarity:	121/259 - (46%)	Gaps:	34/259 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QNQSESAIE-----------------PRIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHVI 73
            ||.|.|.:.                 ||:|||::|....:|.|:|::...:|.|||.|:....::
Mouse   175 QNGSRSCLSGSLVSLRCLDCGKSLKTPRVVGGVEAPVDSWPWQVSIQYNKQHVCGGSILDPHWIL 239

  Fly    74 TAGHCVKHGNDVVPADLWSIQAGSLLLSSDGVRIPVAEV-IMHPNYATGGHNDLAVLRLQSPLTF 137
            ||.||.:...||   ..|.::|||.:| .:...:|||:: |..||.......|:|:::||.||||
Mouse   240 TAAHCFRKYLDV---SSWKVRAGSNIL-GNSPSLPVAKIFIAEPNPLYPKEKDIALVKLQMPLTF 300

  Fly   138 DANIAAIQLATEDPPNCVA--VDISGWGNIAEK-GPLSDSLL--FVQVTSISRGACRWMFYSRLP 197
            ..::..|.|...|.....|  |.:.|||...|. |.:||.||  .|||...:|......:...:.
Mouse   301 SGSVRPICLPFSDEVLVPATPVWVIGWGFTEENGGKMSDMLLQASVQVIDSTRCNAEDAYEGEVT 365

  Fly   198 ETMICL-LHSKNSGACYGDSGGPATYGG---KVVGLASLLLGGGC-GRAAPDGYLRISKVRAWI 256
            ..|:|. ........|.||||||..|..   :|||:.|  .|.|| |.:.|..|.:::....||
Mouse   366 AEMLCAGTPQGGKDTCQGDSGGPLMYHSDKWQVVGIVS--WGHGCGGPSTPGVYTKVTAYLNWI 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	76/230 (33%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	62/188 (33%)
Tmprss4	NP_663378.1	LDLa	56..90	CDD:238060
		SRCR_2	106..195	CDD:295335	4/19 (21%)
		Tryp_SPc	202..427	CDD:214473	76/230 (33%)
		Tryp_SPc	203..430	CDD:238113	77/231 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910