DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and SCRASP2

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_316661.5	Gene:	SCRASP2 / 1277217	VectorBaseID:	AGAP006631	Length:	1343	Species:	Anopheles gambiae

Alignment Length:	261	Identity:	79/261 - (30%)
Similarity:	109/261 - (41%)	Gaps:	53/261 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RIVGGIKAKQGQFPHQISLRLRGEH---YCGGVIISATHVITAGHCVKHGNDVVPADL-----WS 92
            |||||..:..|.:|. |:..|.|..   ||.||:|:...|:||.||:  ||......:     |:
Mosquito  1079 RIVGGSTSNPGDWPF-IAAILGGPEEVFYCAGVLIADQWVLTASHCI--GNSPTSHTMRNVNDWT 1140

  Fly    93 IQAGSLLLSSD---GVRIPVAEVIMHPNYATGGH----NDLAVLRLQSPLTFDANIAAIQLATED 150
            ||.|.....|.   |.::.|..||.||.|..  |    ||:|:.:|.:.:.|..::..:.|   .
Mosquito  1141 IQLGITRRRSHTYYGQKVKVKTVIPHPMYNL--HIPHDNDIALFQLATRVAFHEHLLPVCL---P 1200

  Fly   151 PP---------NCVAVDISGWGNIAEKGPLSDSLLF------VQVTSISRGAC-RWMFYSRLPET 199
            ||         ||..|   |||...|:....:...:      |.|..:||..| .|:....:.|.
Mosquito  1201 PPHIRELPTGINCTVV---GWGKREERNSTPNGASYEPTLNEVNVPIVSRELCIDWLETFNVTEG 1262

  Fly   200 MICLLHSKNS-GACYGDSGGP--ATYGGK-----VVGLASLLLGGGCGR-AAPDGYLRISKVRAW 255
            |||..:.:.. .||.||||||  ..|..:     |.|:.|  .|..|.. ..|..|..:.|...|
Mosquito  1263 MICAGYQEGGRDACQGDSGGPLLCPYPNEKDRWFVGGIVS--WGVRCAHPKLPGVYANVPKFIPW 1325

  Fly   256 I 256
            |
Mosquito  1326 I 1326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	77/259 (30%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	65/213 (31%)
SCRASP2	XP_316661.5	Fz	753..857	CDD:279700
		LDLa	889..918	CDD:238060
		LDLa	921..955	CDD:294076
		SRCR_2	956..>1011	CDD:295335
		Tryp_SPc	1079..1326	CDD:214473	77/259 (30%)
		Tryp_SPc	1080..1326	CDD:238113	76/258 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910