DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and SCRASP1

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_315638.3	Gene:	SCRASP1 / 1276311	VectorBaseID:	AGAP005625	Length:	1322	Species:	Anopheles gambiae

Alignment Length:	251	Identity:	75/251 - (29%)
Similarity:	112/251 - (44%)	Gaps:	43/251 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHVITAGHCVKHGNDVVPADLWSIQAGSLLL 100
            |:|.|.:...|..|.|.|||::..|:||.|:|:..||:||.||:..    .|...:.::.|....
Mosquito  1078 RVVHGSETVYGHHPWQASLRVKTMHWCGAVLITRYHVLTAAHCLIG----YPKSTYRVRIGDYHT 1138

  Fly   101 SS-DGVRIP--VAEVIMHPNYATGGH--NDLAVLRLQSPLTFDANIAAIQLATEDPP-----NCV 155
            :: |...:.  :....:|..:..|.|  ||:||:.|::|:.|:..:..|.|...|.|     ||.
Mosquito  1139 AAYDNAELDIFIENTYIHEQFREGHHMSNDIAVVVLKTPVRFNDYVQPICLPARDAPYLPGQNCT 1203

  Fly   156 AVDISGWGNIAEKGPLSDS--LLFVQVTSISRGACR--WMFYSRLPETMICLLHSKNSG------ 210
               ||||| ..|.|....|  |....|..:....||  .::...|.:.|.|      :|
Mosquito  1204 ---ISGWG-ATEAGSKDSSYDLRAGTVPLLPDSVCRRPEVYGDSLIDGMFC------AGTLEPGV 1258

  Fly   211 -ACYGDSGGPATYGGK-----VVGLASLLLGGGCGRA-APDGYLRISKVRAWIAEK 259
             :|.||||||......     :.|:.|  .|..||.| .|..||:::..|.||.:|
Mosquito  1259 DSCDGDSGGPLVCPNSEGLHTLTGIVS--WGKHCGYANKPGVYLKVAHYRDWIEQK 1312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	72/246 (29%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	59/202 (29%)
SCRASP1	XP_315638.3	ChtBD2	181..228	CDD:214696
		ChtBD2	289..334	CDD:214696
		LDLa	731..762	CDD:238060
		SRCR	776..878	CDD:278931
		SR	776..877	CDD:214555
		LDLa	884..921	CDD:238060
		SR	927..1025	CDD:214555
		SRCR	932..1025	CDD:278931
		Tryp_SPc	1078..1309	CDD:214473	72/246 (29%)
		Tryp_SPc	1079..1312	CDD:238113	73/248 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910