DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and AgaP_AGAP008808

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_557970.3	Gene:	AgaP_AGAP008808 / 1275666	VectorBaseID:	AGAP008808	Length:	574	Species:	Anopheles gambiae

Alignment Length:	280	Identity:	82/280 - (29%)
Similarity:	121/280 - (43%)	Gaps:	32/280 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLLLCGVQVILGQDVAQNQSESAIEPR-------IVGGIKAKQGQFP-HQISLRLRG---EHYCG 63
            :|||.|....:.:...|.::......|       |..|:.||.|.:| |.......|   |:.||
Mosquito    10 VLLLFGFLYFMSRACGQEENYLTCGRRKVQSVFLIHNGVDAKAGHWPWHAAIFHGNGRQEEYQCG 74

  Fly    64 GVIISATHVITAGHCVKHGNDVVPADLWSIQAGSLLL--SSDGVRI-PVAEVIMHPNYATGG-HN 124
            |.|:....::||.|||.....|:.|...|:..|.:.|  :|:..:| .|.::|:||.:.:.. :|
Mosquito    75 GSILDQNTILTASHCVYTHKSVISAARVSVHVGQIHLKETSEYTQIHGVQDIILHPEFNSNSFNN 139

  Fly   125 DLAVLRLQSPLTFDANIAAIQLATEDPPNCVAV----DISGWGNIAEKGPLSDSLLFVQVTSISR 185
            |:|:|:|.:.:|....:..:.|.|.|....:.|    .|.|:| :.|...:||.|....|..:..
Mosquito   140 DIALLKLSTNITMTKYVQPVCLWTMDSNQEMIVGKNGTIVGFG-LNEHDVVSDQLKQALVGVVDA 203

  Fly   186 GAC----RWMFYSRLPETMICLLHSKNSGACYGDSGGPATY--GGK--VVGLASLL-LGGGCGRA 241
            ..|    |..|...|...|.|.......|||.|||||...:  |||  |.||.|.. |.|..|..
Mosquito   204 LTCIKSDRAAFGPVLTSEMFCGKGRTGVGACNGDSGGGMFFEVGGKWFVRGLVSFTPLRGNTGLC 268

  Fly   242 AP---DGYLRISKVRAWIAE 258
            .|   ..|..::|...||.:
Mosquito   269 DPLKYTAYTDVAKYLEWIKQ 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	75/250 (30%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	60/197 (30%)
AgaP_AGAP008808	XP_557970.3	Tryp_SPc	44..288	CDD:238113	76/244 (31%)
		Tryp_SPc	46..286	CDD:214473	73/240 (30%)
		Tryp_SPc	324..566	CDD:304450
		Tryp_SPc	330..566	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910