DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and AgaP_AGAP008558

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_314667.4	Gene:	AgaP_AGAP008558 / 1275424	VectorBaseID:	AGAP008558	Length:	574	Species:	Anopheles gambiae

Alignment Length:	241	Identity:	64/241 - (26%)
Similarity:	102/241 - (42%)	Gaps:	23/241 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 IVGGIKAKQGQFPHQISLRLRGE----HYCGGVIISATHVITAGHCVKHGNDVVPADLWSIQAGS 97
            |:||..|..||:|...::..|.|    :.|||.||:...::||.|||:....|:..|..|:|.|.
Mosquito    37 ILGGEDAISGQWPWHAAIFHRIERSFMYQCGGAIINQNTILTAAHCVQLNQGVITVDRLSVQVGR 101

  Fly    98 LLL---SSDGVRIPVAEVIMHPNY-ATGGHNDLAVLRLQSPLTFDANIAAIQL---ATEDPPNCV 155
            ..|   .|.........:|:|..| |....||:|:::|.:.:.|...:..:.|   |..|....:
Mosquito   102 TYLYAAESHTQEHQAERIIVHEEYSAAQVRNDIALIKLATDIRFTEYVQPVCLWDRARTDIGQLI 166

  Fly   156 --AVDISGWGNIAEKGPLSDSLLFVQVTSISRGAC----RWMFYSRLPETMICLLHSKNSGACYG 214
              ...:.|:| |.|.|.::|.|....:..:....|    |.:|...|...:.|......:..|.|
Mosquito   167 GRVGTVIGFG-ITEIGEVADRLRVAYMPIVDTQTCLESNRNLFGRVLTRNVFCAGFRNGTTVCGG 230

  Fly   215 DSGGPATYGGK----VVGLASLLLGGGCGRAAPDGYLRISKVRAWI 256
            ||||...:..:    :.|:.| ..|..|..|...|:..::....||
Mosquito   231 DSGGGMYFEIENRWYIRGIVS-FSGQNCQSADFAGFSDVATYLDWI 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	62/239 (26%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	55/198 (28%)
AgaP_AGAP008558	XP_314667.4	Tryp_SPc	37..277	CDD:238113	64/241 (27%)
		Tryp_SPc	37..275	CDD:214473	62/239 (26%)
		Tryp_SPc	322..568	CDD:214473
		Tryp_SPc	322..568	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910