DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and AgaP_AGAP010545

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_314514.4	Gene:	AgaP_AGAP010545 / 1275276	VectorBaseID:	AGAP010545	Length:	876	Species:	Anopheles gambiae

Alignment Length:	226	Identity:	64/226 - (28%)
Similarity:	104/226 - (46%)	Gaps:	31/226 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 CGGVIISATHVITAGHCVKHGNDVVPADLWSIQAGSLLLSSD-----GVRIPVAEVIMHPNYA-T 120
            |||.:|....:|||.||..:.::|.| |:  ::.|.|.:.||     ..::.:..:|.||.|: :
Mosquito    47 CGGSLIWNNFIITAAHCTANDDNVSP-DV--VRFGDLNIYSDEDDRYAQQLTIVSIIRHPKYSFS 108

  Fly   121 GGHNDLAVLRLQSPLTFDANIAAIQLATEDPPNCVAVDISGWGNIAEKGPLSDSLLFVQVTSISR 185
            ..:.|:|:::|.:.::....:|...|..:.......::.:|||........:..||.:.:..:|.
Mosquito   109 ARYYDIALMKLDNNVSVHETVAPACLWLDKEVRFKELESAGWGQTGFGESPTPILLKITLKPMSN 173

  Fly   186 GACRWMFYSR--------LPETMICLLHSKNSGACYGDSGGP----ATYGGKV----VGLASLLL 234
            ..|...:.|.        |.:..||...:| ...|.||||||    ..:..||    |||.|  .
Mosquito   174 ENCTEHYTSTTVRGLQRGLDQHHICAGDAK-MDTCLGDSGGPLHIRLQHNYKVTPFLVGLTS--F 235

  Fly   235 GGGCGRAAPDGYLRISKVRAWIAE---KAGL 262
            |..||::.|..|.||:..|:||.|   |.||
Mosquito   236 GRPCGQSHPGVYTRIAPFRSWIVETLQKNGL 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	58/215 (27%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	42/170 (25%)
AgaP_AGAP010545	XP_314514.4	Trypsin	21..257	CDD:278516	58/215 (27%)
		Tryp_SPc	47..260	CDD:238113	60/218 (28%)
		Tryp_SPc	336..544	CDD:304450
		Tryp_SPc	677..867	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910