DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and AgaP_AGAP004149

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_313033.3	Gene:	AgaP_AGAP004149 / 1273976	VectorBaseID:	AGAP004149	Length:	543	Species:	Anopheles gambiae

Alignment Length:	307	Identity:	76/307 - (24%)
Similarity:	116/307 - (37%)	Gaps:	105/307 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LCGVQVILGQDVAQNQSESAIEPRIVGGIKAKQGQFPHQISLRLRGE------HYCGGVIISATH 71
            |||:               ::..||:||.....||||....|..|.:      :.|.|.:|:..|
Mosquito   273 LCGL---------------SVNTRIIGGETEVPGQFPWMARLAYRNQTSGRVTYRCAGSLITNRH 322

  Fly    72 VITAGHCVKHGNDVVPADLWSIQAGSLLLSSDGVRIP----------VAEVIMH-----PNYATG 121
            |||..|||.  |.:....|.||:.|.  |..:.|..|          :.::|.|     |.||
Mosquito   323 VITVAHCVT--NLIDELQLVSIRLGD--LECNAVTDPRCSARYQDFAIEQIIPHESYDVPKYA-- 381

  Fly   122 GHNDLAVLRLQSPLTFDANIAAIQLATEDPPNCVAVD---------------ISGWGNIAEKGPL 171
              ||:|:::|:. .|...||.:        |.|:..|               |:|||:.:.:...
Mosquito   382 --NDIALIKLRE-TTETYNIIS--------PLCLPTDQYAPYALNLTGQLGIIAGWGSTSNRSNT 435

  Fly   172 -SDSLLFVQVTSISRGAC-----RWMFYSRLP----ETMICLLHSKNSGACYGDSGGP------- 219
             |.:|.::::..:....|     |:...||.|    ...:|....:|..||.||||||
Mosquito   436 PSPTLQWLRLPIVDTAGCANAYARYSVNSRNPIIVSGNQMCAQGQENRDACQGDSGGPLMNEAIS 500

  Fly   220 ----------ATYGGKVVGLASLLLGGGCGRAAPDGYLRISKVRAWI 256
                      .::|.:..|:::.          |..|.|||....||
Mosquito   501 TRDRFVLLGLVSFGPRTCGVSNF----------PGVYTRISAYIDWI 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	71/282 (25%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	61/227 (27%)
AgaP_AGAP004149	XP_313033.3	CLIP	47..92	CDD:288855
		Tryp_SPc	281..537	CDD:214473	71/282 (25%)
		Tryp_SPc	282..537	CDD:238113	70/281 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910