DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and AgaP_AGAP003748

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_310280.7	Gene:	AgaP_AGAP003748 / 1271480	VectorBaseID:	AGAP003748	Length:	547	Species:	Anopheles gambiae

Alignment Length:	282	Identity:	62/282 - (21%)
Similarity:	111/282 - (39%)	Gaps:	57/282 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 QDVAQNQSESAIEPRIVGGIKAKQGQFPHQISLRLRG--------EHYCGGVIISATHVITAGHC 78
            :||:     ||:...|.||.:|...:|||..::....        ::.|||.:|:|.:|:||.||
Mosquito    44 EDVS-----SALGFFIFGGRRAFLKEFPHMAAIGWTDKTVSPPVVQYKCGGSLIAAKYVLTAAHC 103

  Fly    79 VKHGND------VVPADLWSIQAGSLLLSSD---GVRIPVAEVIMHPNYATG-GHNDLAVLRLQS 133
             |..::      |:|.|...:...:|..:.|   ..:..:....:|..:... .:.|:|::.|..
Mosquito   104 -KVDDEKYVFIRVIPPDTVRLGDTNLATTEDDETAQQFKIVSFAVHEKFKKNRKYYDIALIELDR 167

  Fly   134 PLTFDANIAAIQLATEDPPNCVAVDIS--GWGNIAEKGPLSDSLLFVQVTSISRGACRWMFYSRL 196
            ...|:..:..|.|...|..:..:..:.  |:|.......:|.:|..|.:......:|.    :.|
Mosquito   168 EAKFNTAVCPICLWPLDNIHEYSSSLRAIGFGFTTYTSGMSPTLQKVSLNYYDSDSCN----NEL 228

  Fly   197 PE----------TMICLLHSKNSGACYGDSGGP-----------ATYGGKVVGLASLLLGGGCGR 240
            |:          ...| ..:.:..||.||||||           ..|   :.|:.|  .|.||..
Mosquito   229 PKDARLRYGLTSDQFC-TKTPHKDACLGDSGGPLQIDLSDVTRTIPY---LTGVVS--FGTGCWD 287

  Fly   241 AAPDGYLRISKVRAWIAEKAGL 262
            .:...|.:::....||.|:..:
Mosquito   288 GSMGVYTKVASYINWIRERVNV 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	55/260 (21%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	46/211 (22%)
AgaP_AGAP003748	XP_310280.7	Tryp_SPc	54..305	CDD:238113	57/261 (22%)
		Tryp_SPc	54..303	CDD:214473	55/259 (21%)
		Trypsin	316..521	CDD:278516
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910