DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and AgaP_AGAP011325

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_309327.4	Gene:	AgaP_AGAP011325 / 1270612	VectorBaseID:	AGAP011325	Length:	631	Species:	Anopheles gambiae

Alignment Length:	319	Identity:	79/319 - (24%)
Similarity:	119/319 - (37%)	Gaps:	86/319 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 WTTLWTVLLLLLCGVQ------VILGQDVAQNQSESA-------------IEPRIVGGIKAKQGQ 47
            ||..|  |..:..|::      |...|:...|.....             ||.:|..||.|...|
Mosquito   333 WTIPW--LGFVRVGIEDEPRCAVCCQQEADSNNHRKRNLTLLDLEKCGPYIEEKIANGIDAILFQ 395

  Fly    48 FPHQISLR-LRGEHYCGGVIISATHVITAGHCVKHGNDVVPADLWSIQAGSLLLSSD------GV 105
            :|....|: ......|||.:|:..:|:||.||.:.....:     |::.|...|.||      |.
Mosquito   396 YPWMALLQDTELAFVCGGTLINKRYVLTAAHCFREKLSKI-----SVRLGEFDLKSDIDCDKRGE 455

  Fly   106 R-------IPVAEVIMHPNYATGGH--NDLAVLRLQSPLTFDANIAAIQLATEDPPNCVAVD--- 158
            |       |.|...|.|.:| :..|  ||:|::||.|..:::.|:.         |.|:.|.
Mosquito   456 RCALPPQDIAVERTIKHKDY-SARHKVNDIALIRLASEASYNENVM---------PICLPVSPEM 510

  Fly   159 --------ISGWGNIAEKGPLSDSLLFVQVTSISRGACRWMF-----YSRLPETMICLLHSKNSG 210
                    :|||| :.|....||.|....:..:....|:.:.     |..:....:|.:.:..:.
Mosquito   511 RTVKEIYYVSGWG-LTENDTSSDVLQVGLLRQLPNDVCQQLLQRKDKYVTVNSDQMCAIGANRTD 574

  Fly   211 ACYGDSGGP----------ATYGGKVVGLASLLLGGGCGR-AAPDGYLRISKVRAWIAE 258
            .|.||||||          ..||....||.:      ||: .||..|.|:.....||.:
Mosquito   575 NCSGDSGGPLKTVAVNARFVQYGVVSYGLRT------CGKETAPGVYTRVENYIDWILD 627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	67/262 (26%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	55/213 (26%)
AgaP_AGAP011325	XP_309327.4	Tryp_SPc	44..287	CDD:238113
		Tryp_SPc	46..286	CDD:214473
		Tryp_SPc	384..625	CDD:214473	67/262 (26%)
		Tryp_SPc	385..625	CDD:238113	67/261 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910