DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and AgaP_AGAP007043

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_001237132.2	Gene:	AgaP_AGAP007043 / 1270058	VectorBaseID:	AGAP007043	Length:	575	Species:	Anopheles gambiae

Alignment Length:	298	Identity:	77/298 - (25%)
Similarity:	125/298 - (41%)	Gaps:	73/298 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VLLLL---------LCGVQVILGQDVAQNQSESAIEPR--IVGGIKAKQGQFPHQISL--RLRGE 59
            ||||:         .|||:              .:.|.  :..||.|:.|.:|..::|  .::.|
Mosquito    21 VLLLIQQPFEVAASTCGVR--------------RLSPMGLVTKGIIAEPGDWPWHVALFAHMKSE 71

  Fly    60 ---HYCGGVIISATHVITAGHCVKHGNDVVPADLWSIQAGSLLLSSDG----VRIPVAEVIMHPN 117
               :.|||.|||...|::|.||:|..|    .|.:.::||...|::|.    |...:.|:|:||.
Mosquito    72 KPAYKCGGSIISQHFVLSAAHCIKEPN----PDHYFLKAGIHHLNNDNDTSVVVYNLFEIILHPK 132

  Fly   118 YATGG-HNDLAVLRLQSPLTFDANIAAIQLATEDPPNCVAVDISGWGNIA------EKGPLSDSL 175
            |.... :||:|::|....::| |:.:...:......|...:|:.....||      |...:|::|
Mosquito   133 YDRHTFYNDIALMRPDRAISF-ASFSIFPICLWPTHNATLIDVLSRSGIAVGFGFDETHRISETL 196

  Fly   176 LFVQVTSISRGACRWMFYSRLPETM---------ICLLHSKNSGA--CYGDSGGPATYG------ 223
            ....:..|.:..|    ..:|||.:         :|.:.:: |||  |.|||||...:.
Mosquito   197 QQASMKVIEKQQC----IEQLPEHVRFLPQDAGKMCAIGTE-SGANVCSGDSGGGLYFAKDQVWY 256

  Fly   224 --GKVVGLASLLLGGG---CGRAAPDGYLRISKVRAWI 256
              |.|...|...|..|   |..|.|..|..:::...||
Mosquito   257 LRGIVSAAARRDLDTGEATCNAALPATYTDVAQYTTWI 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	67/259 (26%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	57/208 (27%)
AgaP_AGAP007043	XP_001237132.2	Tryp_SPc	50..297	CDD:238113	69/255 (27%)
		Tryp_SPc	50..294	CDD:214473	67/253 (26%)
		Tryp_SPc	330..573	CDD:304450
		Tryp_SPc	330..570	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910