DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and AgaP_AGAP013252

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_003436670.1	Gene:	AgaP_AGAP013252 / 11175997	VectorBaseID:	AGAP013252	Length:	597	Species:	Anopheles gambiae

Alignment Length:	243	Identity:	59/243 - (24%)
Similarity:	101/243 - (41%)	Gaps:	25/243 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 GIKAKQGQFPHQISLRLRG----EHYCGGVIISATHVITAGHCVKHGNDVVPADLWSIQAGSLLL 100
            |.:.|:|.:|...::..|.    |:.|||.|:....::||.||:.....::..|..|:|.|...|
Mosquito    48 GTETKEGHWPWHTAIYHREQTNFEYVCGGSILDRNTILTAAHCLYTSRGLIKLDQLSVQVGRNQL 112

  Fly   101 SSDGVRIP---VAEVIMHPNYATGG-HNDLAVLRLQSPLTFDANIAAIQLATEDPPNCVAV---- 157
            |...||..   ..::|:||.::... .:|:|:::|.:.:|....:..:.|.:.:|...:.|
Mosquito   113 SEASVRSQEHHPEQLIVHPGFSPNSVTDDIALIKLATDITMTRYVQPVCLWSLEPNLDLIVGRNG 177

  Fly   158 DISGWGNIAEKGPLSDSLLFVQVTSISRGAC----RWMFYSRLPETMICLLHSKNSGACYGDSG- 217
            .:.|:| :.|...:||.|....:..:....|    |.::...|...|.|.........|.||||
Mosquito   178 TVVGFG-LTEHDRVSDYLRQAAIAVVDSWTCIESDRQVYGVTLTANMYCGGGKTGVSVCNGDSGG 241

  Fly   218 ------GPATYGGKVVGLASLLLGGG-CGRAAPDGYLRISKVRAWIAE 258
                  |...|...||....|....| |.......:..::|.|.||.:
Mosquito   242 GMFFEHGDTWYVRGVVSFMPLRENVGLCDGTKYTVFTDVAKYRDWIGQ 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	57/239 (24%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	48/201 (24%)
AgaP_AGAP013252	XP_003436670.1	Tryp_SPc	47..287	CDD:214473	57/239 (24%)
		Tryp_SPc	48..287	CDD:238113	57/239 (24%)
		Tryp_SPc	334..575	CDD:214473
		Tryp_SPc	335..575	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910