DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and tmprss2.15

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_031752206.1	Gene:	tmprss2.15 / 101732233	XenbaseID:	XB-GENE-22065943	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	266	Identity:	83/266 - (31%)
Similarity:	124/266 - (46%)	Gaps:	38/266 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLLLCGVQVILGQDVAQNQSESAIEPRIVGGIKAKQGQFPHQIS-LRLRGE--HYCGGVIISAT 70
            |..:.||:             .:.::.|||||..|..|.:|.|:. |:|.|.  :.|||.||:..
Frog   250 LRCISCGL-------------STKVDSRIVGGTPASVGDWPWQVELLKLVGTSIYLCGGSIITPH 301

  Fly    71 HVITAGHCVKHGNDVVPADLWSIQAGSLLLSS-DGVRIPVAEVIMHPNYATGGH-NDLAVLRLQS 133
            .::||.||| :|:...|: .:.:.||||.:.| ......|...::||:|::... .|:|:|:|.:
Frog   302 WIVTAAHCV-YGSTSTPS-AFKVFAGSLTIQSYYSAGYTVERALVHPSYSSYTQIYDVALLKLTA 364

  Fly   134 PLTFDANIAAIQLATEDPP-----NCVAVDISGWGNIAEKGPLSDSLLFVQVTSISRGACRW--M 191
            .|.|..|:..:.|.....|     .|.   |||||..||.|.:|.:|:...|..||...|..  :
Frog   365 ALVFTTNLRPVCLPNVGMPWAEGQPCW---ISGWGTTAEGGSISKNLMAASVPIISSTTCNQAAV 426

  Fly   192 FYSRLPETMICLLH-SKNSGACYGDSGGPATYGGK----VVGLASLLLGGGCGRA-APDGYLRIS 250
            :...:..||:|..: |..:..|.||||||......    :||..|  .|.||.|| .|..|..::
Frog   427 YGGAISSTMMCAGYLSGGTDTCQGDSGGPLVTKTNSLWWLVGDTS--WGYGCARAYKPGVYGNVT 489

  Fly   251 KVRAWI 256
            ....||
Frog   490 VFIEWI 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	78/237 (33%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	65/194 (34%)
tmprss2.15	XP_031752206.1	LDLa	93..121	CDD:238060
		SRCR_2	164..259	CDD:406055	3/21 (14%)
		Tryp_SPc	265..498	CDD:238113	79/238 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910