DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and tmprss2.12

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_031752400.1	Gene:	tmprss2.12 / 100497514	XenbaseID:	XB-GENE-22065925	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	239	Identity:	75/239 - (31%)
Similarity:	114/239 - (47%)	Gaps:	23/239 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 EPRIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHVITAGHCVKHGNDVVPADLWSIQAGSL 98
            |.|||||..|..|.:|.|::|:....:.|||.:|:|..::||.|||:  .|.....||....|.:
Frog   258 ESRIVGGSSASIGDWPWQVNLQYDDTNLCGGSVIAANWIVTAAHCVQ--GDTSSPSLWKAFIGKI 320

  Fly    99 LLSS--DGVRIPVAEVIMHPNYAT-GGHNDLAVLRLQSPLTFDANIAAIQLAT-----EDPPNCV 155
            .:.|  |.....|..:|:||:|:: ...||:|:::|::.:.|.:....:.|..     |:...|.
Frog   321 KMPSYYDSSAYSVDRIIVHPDYSSQTNSNDIALMKLKTSIAFSSISRPVCLPNYGMQWEEGQPCY 385

  Fly   156 AVDISGWGNIAEKGPLSDSLLFVQVTSISRGACRW--MFYSRLPETMICLLHSKNS-GACYGDSG 217
               |||||..::||.:|..|.:..|..||...|..  |:...:..:|||..:.|.. .:|.||||
Frog   386 ---ISGWGTTSQKGSISSVLKYAMVPLISPTTCNQTIMYNGAITSSMICAGYPKGGVDSCQGDSG 447

  Fly   218 GPATYGGK----VVGLASLLLGGGCGRA-APDGYLRISKVRAWI 256
            ||......    :||..|  .|.||... .|..|..::....||
Frog   448 GPLVTKTNSLWWLVGDTS--WGDGCANVYRPGVYGNMTVFLQWI 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	72/235 (31%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	61/192 (32%)
tmprss2.12	XP_031752400.1	LDLa	127..155	CDD:238060
		SRCR_2	160..255	CDD:406055
		Tryp_SPc	261..489	CDD:238113	71/234 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910