DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and prss12

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_002934300.3	Gene:	prss12 / 100495119	XenbaseID:	XB-GENE-984837	Length:	851	Species:	Xenopus tropicalis

Alignment Length:	282	Identity:	78/282 - (27%)
Similarity:	130/282 - (46%)	Gaps:	54/282 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLCGVQVILGQDVAQNQSESAIEPRIVGGIKAKQGQFPHQISLRLRGEH-----YCGGVIISATH 71
            |:||.::       |::...    ||:||..:.:|.:|.|::|||:..|     .||..:||:..
Frog   593 LVCGSRL-------QHRRPK----RIIGGKNSVRGGWPWQVALRLKSSHGDGRLLCGATLISSCW 646

  Fly    72 VITAGHCVK-HGNDVVPADLWSIQAG---SLLLSSDGVRIPVAEVIMHPNYATGGHN-DLAVLRL 131
            |:||.||.| :||:   ...:.|:.|   :|:.......:.:.::|:|.:|...|:: |:|::||
Frog   647 VLTAAHCFKRYGNN---TRSYVIRVGDYHTLVPEEYEEDMTIQQIIIHNDYRPDGNDYDIALIRL 708

  Fly   132 QSPLTFDANIAAIQLATEDPPNCVAVD------------ISGWGNIAEKGPLSDSLLFVQVTSIS 184
            .....     ..:||:|...|.|:.:.            |:|||:...  ..|.:|....||.:.
Frog   709 HGTAE-----QCVQLSTHVLPACLPLRRERPQKTASNCYITGWGDTGR--AYSRTLQQATVTLLP 766

  Fly   185 RGACRWMFYSRLPETMIC---LLHSKNSGACYGDSGGPAT---YGGK--VVGLASLLLGGGCG-R 240
            :..|...:.|:....|:|   :...|:..:|.||||||..   .||.  |.|:.|  .|.||| :
Frog   767 KRVCEERYRSQFTGRMLCAGSVKTQKHVDSCQGDSGGPLVCERSGGSWIVYGVTS--WGYGCGVK 829

  Fly   241 AAPDGYLRISKVRAWIAEKAGL 262
            .:|..|.::|....||.....|
Frog   830 DSPGVYTKVSAFIPWIKSVTNL 851

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	71/250 (28%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	56/206 (27%)
prss12	XP_002934300.3	KR	78..140	CDD:412161
		SRCR	148..244	CDD:395421
		SR	257..356	CDD:214555
		SR	363..461	CDD:214555
		SR	476..575	CDD:214555
		Tryp_SPc	607..848	CDD:238113	72/252 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910