DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and f12

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_017947702.2	Gene:	f12 / 100493769	XenbaseID:	XB-GENE-1004811	Length:	597	Species:	Xenopus tropicalis

Alignment Length:	250	Identity:	67/250 - (26%)
Similarity:	104/250 - (41%)	Gaps:	28/250 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 QSESAIEPRIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHVITAGHCVKHGNDVVPADLWS 92
            |...:|.||||||:.|.....|:..:|.: ..|:|||.:||...::||.||:....:|....:..
Frog   350 QKTPSIMPRIVGGLVALPASHPYIAALYI-DNHFCGGSLISPCWIVTAAHCLDQRPNVTKISVVL 413

  Fly    93 IQAGSLLLSSDGVRIPVAEVIMHPNY--ATGGHNDLAVLRLQS-----PLTFDANIAAIQL---- 146
            .|:.........|.:.|.:.|:|..|  .|..| |:|:::::|     ...|...:..|.|
Frog   414 GQSRFNTTDQHTVTLLVEKYILHEKYYGDTLQH-DIALVKVKSINGLCASEFSQFVQPICLPQQF 477

  Fly   147 -ATEDPPNCVAVDISGWGNIAEKGPLSDSLLFVQVTS---ISRGACR--WMFYSRLPETMICLLH 205
             ..|....||   ::|||:..|..  .....|:|..|   |....|:  .:...|:...|:|...
Frog   478 KMAESTKQCV---VAGWGHQYEGA--EHYAFFLQEASMPIIPYTQCQSPSVHGDRMLPGMLCAGF 537

  Fly   206 SKNS-GACYGDSGGP--ATYGGKVVGLASLLLGGGCGRA-APDGYLRISKVRAWI 256
            .:.. .||.||||||  ....|::.....:..|.||... .|..|..::....||
Frog   538 MEGGVDACQGDSGGPLVCEVDGRIELHGVVSWGSGCAEENKPGVYTAVTSYTDWI 592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	62/240 (26%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	53/199 (27%)
f12	XP_017947702.2	fn2	46..87	CDD:394995
		EGF_CA	95..129	CDD:238011
		KR	213..298	CDD:214527
		Tryp_SPc	359..595	CDD:238113	62/240 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910