DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and tmprss6

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_004913946.2	Gene:	tmprss6 / 100489045	XenbaseID:	XB-GENE-1011573	Length:	806	Species:	Xenopus tropicalis

Alignment Length:	258	Identity:	81/258 - (31%)
Similarity:	132/258 - (51%)	Gaps:	33/258 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 CGVQVILGQDVAQNQSESAIEPRIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHVITAGHC 78
            ||:|              |:..|:|||.:|::|::|.|.||::||||.|||.:::...::||.||
Frog   562 CGIQ--------------AVGIRLVGGTQAQEGEWPWQASLQVRGEHICGGTLVADQWILTAAHC 612

  Fly    79 VKHGNDVVPADLWSIQAGSLLLS---SDGVRIPVAEVIMHPNYATGGHN-DLAVLRLQS--PLTF 137
            ....:...| ::|::..|.:.||   ...:...|..:::||.|....|: |:|::.|..  |||
Frog   613 FTPESYASP-EVWTVYLGKVRLSRSTQKELAFKVIRLVIHPFYDEDSHDYDVALVLLDHLVPLT- 675

  Fly   138 DANIAAIQL--ATEDPPNCVAVDISGWGNIAEKGPLSDSLLFVQVTSISRGACRWMFYSRLPETM 200
            ..::..|.|  :|...|...:..::|||::.|.||.||.|..|.:..:::..|..::..::...|
Frog   676 SPHVQPICLPSSTHHFPTGSSCWVTGWGSVKENGPTSDVLQKVDIQLVAQDICTELYRYQISPRM 740

  Fly   201 ICLLHSKNS-GACYGDSGGP---ATYGGK--VVGLASLLLGGGCGRAAPDG-YLRISKVRAWI 256
            :|..:...| .||.||||.|   .|..|:  ..||.|  .|.|||.....| |.||:::..||
Frog   741 LCAGYRDGSKDACQGDSGSPLVCKTASGRWFQAGLVS--WGAGCGIPRYFGVYSRITRLVQWI 801

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	75/234 (32%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	60/190 (32%)
tmprss6	XP_004913946.2	SEA	77..176	CDD:396113
		CUB	235..303	CDD:412131
		LDLa	448..478	CDD:238060
		LDLa	480..514	CDD:238060
		LDLa	525..560	CDD:238060
		Tryp_SPc	572..804	CDD:238113	76/234 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910