DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and klkb1

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_002934450.3	Gene:	klkb1 / 100486524	XenbaseID:	XB-GENE-985051	Length:	629	Species:	Xenopus tropicalis

Alignment Length:	277	Identity:	89/277 - (32%)
Similarity:	139/277 - (50%)	Gaps:	50/277 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLLCGVQVILGQDVAQNQSESAIEP-----RIVGGIKAKQGQFPHQISLRLR-----GEHYCGGV 65
            |.||.::.:.|          ..||     |||||..:..|::|.|:|:.||     .:|.|||.
Frog   370 LRLCKIKSVKG----------CGEPIEHANRIVGGTDSVLGEWPWQVSMHLRLTASYKKHACGGS 424

  Fly    66 IISATHVITAGHC-VKHGNDVVPADLWSIQAGSLLLSSDGVRIPVAE---VIMHPNYATGGH-ND 125
            |||...::||.|| ..|   .:| .:|.|.:|.:.||:.....|.:|   :|:||:|...|: .|
Frog   425 IISNQWIVTAAHCFAMH---PLP-QMWIIYSGVVKLSNITQSTPFSETEQIIIHPHYTGAGNGTD 485

  Fly   126 LAVLRLQSPLTFDANIAAIQLATEDP----PNCVAVDISGWGNIAEKGPLSDSLLFVQVTSISRG 186
            :|:|:|::|::|:.:..||.|...:|    ||  :..|:|||...|.|.|::.|...:|..||..
Frog   486 IALLKLKTPISFNDHQKAICLPPREPTFVLPN--SCWITGWGFTEESGSLANILQKAEVPQISTE 548

  Fly   187 ACRWMF-YSRLPETMICLLHSKNS-GACYGDSGGPAT-------YGGKVVGLASLLLGGGCGRAA 242
            .|:..: .:|:.:.::|..:.:.. .:|.||||||..       |   :.|:.|  .|.||.|..
Frog   549 ECQGNYEQTRIDKKILCAGYKRGKIDSCKGDSGGPLACVVDEIWY---LTGITS--WGEGCARPG 608

  Fly   243 PDG-YLRISKVRAWIAE 258
            ..| |.|:|:...||.|
Frog   609 KPGVYTRVSEFTDWIIE 625

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	80/243 (33%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	66/197 (34%)
klkb1	XP_002934450.3	APPLE	21..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	290..373	CDD:128519	1/2 (50%)
		Tryp_SPc	391..626	CDD:238113	82/246 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910