DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and tmprss3a

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	265	Identity:	89/265 - (33%)
Similarity:	122/265 - (46%)	Gaps:	36/265 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 TVLLLLLCGVQVILGQDVAQNQSESAIEPRIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATH 71
            |.|..:.||             |......|||||..:.:||||.|:||..:.||.|||.||::..
Zfish   281 TALKCIACG-------------SRPKFSARIVGGNLSAEGQFPWQVSLHFQNEHLCGGSIITSRW 332

  Fly    72 VITAGHCVKHGNDVVPADLWSIQAGSLLLSSDGVR-IPVAEVIMHPNYATGG-HNDLAVLRLQSP 134
            ::||.||| :|  :.....|.:.||...|..:.|: ..|.::|.|..|...| .:|:|:::|..|
Zfish   333 ILTAAHCV-YG--IAYPMYWMVYAGLTELPLNAVKAFAVEKIIYHSRYRPKGLDHDIALMKLAQP 394

  Fly   135 LTFDANIAAIQLAT-----EDPPNCVAVDISGWGNIAEKGPLSDSLLFVQVTSISRGACRW--MF 192
            |||:..:..|.|..     ||...|.   |||||...:.|..|.|.....|..||..||..  ::
Zfish   395 LTFNGMVEPICLPNFGEQFEDGKMCW---ISGWGATEDGGDASVSQHCASVPLISNKACSQPEVY 456

  Fly   193 YSRLPETMICLLH-SKNSGACYGDSGGPATYGG----KVVGLASLLLGGGCG-RAAPDGYLRISK 251
            ...|...|||..: ...:.:|.||||||.....    |:||..|  .|.||. :..|..|.||::
Zfish   457 QGYLTAGMICAGYLDGGTDSCQGDSGGPLACEDSSIWKLVGATS--WGQGCAEKNKPGVYTRITQ 519

  Fly   252 VRAWI 256
            ...||
Zfish   520 SLTWI 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	82/234 (35%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	68/191 (36%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845	5/23 (22%)
		Tryp_SPc	298..525	CDD:238113	83/235 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910