Protein Alignment CG11294 and VSX1

DIOPT Version :10

• Sequence 1: NP_572500.1
• Gene: CG11294 / 31807
• FlyBaseID: FBgn0030058
• Length: 261
• Species: Drosophila melanogaster
• Sequence 2: NP_055403.2
• Gene: VSX1 / 30813
• HGNCID: 12723
• Length: 365
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 75/258 - (29%)
• Similarity: 109/258 - (42%)
• Gaps: 63/258 - (24%)

  Fly    12 DLLTEYMFGRRRQRRNRTTFTPQQLQELEALFQKTHYPDVFLREEVALRISLSEARVQVWFQNRR 76
            ||......|:|::||:||.||..||:|||..|.:.|||||:.||.:|::..|.|.|:||||||||
Human   152 DLKASPTLGKRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRR 216

  Fly    77 AKWRKQARLQLLQDAWRMRCLSLGTPPVMGGGAVQGGSG-NGATARPPSQTPENLSSASKDSELA 140
            |||||:      :..|             ||.:|....| .||..|.....|::
Human   217 AKWRKR------EKRW-------------GGSSVMAEYGLYGAMVRHCIPLPDS----------- 251

  Fly   141 EVGNGPNSGSFTMMHPAFQQQHQQQQHQGHQQATDQDKLSKTYTELKLYKAPSHGMELGGMAALS 205
             |.|....|......|.....|::                    .:.:.:.|....:|.|:.. |
Human   252 -VLNSAEGGLLGSCAPWLLGMHKK--------------------SMGMIRKPGSEDKLAGLWG-S 294

  Fly   206 GHSDEGSDGSD------SEEIDLTSG---ACIDFSQSSKLQQQQQQQQQQGTQGAAGSAEANG 259
            .|..|||..|:      |:::...:|   ..||.|.|:: |:.::.....|.||.:.|....|
Human   295 DHFKEGSSQSESGSQRGSDKVSPENGLEDVAIDLSSSAR-QETKKVHPGAGAQGGSNSTALEG 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11294	NP_572500.1	Homeodomain	29..81	CDD:459649	31/51 (61%)
VSX1	NP_055403.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37
		Octapeptide motif	31..38
		PRK14959	<47..>149	CDD:184923
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	113..167		5/14 (36%)
		Nuclear localization signal. /evidence=ECO:0000255	161..166		1/4 (25%)
		Homeodomain	165..221	CDD:459649	34/55 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	290..365		19/69 (28%)