Protein Alignment ldd and ABCA9

DIOPT Version :10

• Sequence 1: NP_001285513.1
• Gene: ldd / 318066
• FlyBaseID: FBgn0083956
• Length: 1998
• Species: Drosophila melanogaster
• Sequence 2: NP_001330984.1
• Gene: ABCA9 / 836295
• AraportID: AT5G61730
• Length: 950
• Species: Arabidopsis thaliana
• Alignment Length: 771
• Identity: 178/771 - (23%)
• Similarity: 294/771 - (38%)
• Gaps: 205/771 - (26%)

  Fly   531 DHEATTISPSSLDGVTTEEVRVTTEQTVVSGDPDLLLLKNEDVLKRSKRQGLFDLLGGFGGSGDA 595
            :..||.||.......::|:.|...|      ||....|....:  .::|:....|:|
plant   152 EKNATVISYGIQTNSSSEKKRGRRE------DPTFKFLVPLQI--AAEREIARSLIG-------- 200

  Fly   596 NKKNKFEVDNMQFYTKQFPYPAFLNDVFKRGLYLAQGVQVAYLLGLVVFVALSV----------- 649
              ..||..|   |..|:|..||...:|.         :...||:|.|.|:|.|:
plant   201 --DPKFSWD---FGFKEFARPAIGGEVI---------ISAFYLMGPVFFLAFSMFGFVLQLGSVV 251

  Fly   650 -RERIWMRESRNSMLMRSMGLKAHSELVAW----ALMSFLELCVIFALISGVLYSGGILGYTNWF 709
             .:.:.:||:     |.:||:...:..::|    .:::|:.  .:|.::.|:::..... ..|.|
plant   252 TEKELKLREA-----MTTMGVYESAYWLSWLIWEGILTFVS--SLFLVLFGMMFQFEFF-LKNSF 308

  Fly   710 ---FMMFYCLSFGLCLISFCYMCTNFFNSANIGAVASALLFFISLCPFIIV---LMFDAKLSVFE 768
               |::|:...|.  :|...:..::..:.::.......|:|.:.....|:.   ..:.:..|:..
plant   309 VLVFLLFFLFQFN--MIGLAFALSSIISKSSSATTVGFLVFLVGFITQIVTTAGFPYSSAYSIGS 371

  Fly   769 SFLVDLSFTTAFAKGWGELIRMELQ--QEGLTVRHLIQVGPARSECAMA------------LLMF 819
            ..:..|.....|:.|...|:.....  ..|::...........|.|.:.            ...|
plant   372 RVIWSLFPPNTFSAGLQLLLEATSSPGDSGISWSERAICAGGESTCVITTNKIYIWLVGTFFFWF 436

  Fly   820 LLDLLLYAVIGLAYQRYKKTDNYSFVK-------------------------------------- 846
            :|.|....:|..| ...:|:..| |:|
plant   437 VLALYFDNIIPNA-SGVRKSIFY-FLKPSYWTGKEGNKVEEGSICSCIGSVPPVEHITPEDEDVL 499

  Fly   847 -----VSRSQLDGKLGASLV-----------NVSKLYGSKC-------AVSNLSLDFARNQVSCL 888
                 |.:..:||::..::.           ..:||...||       ||..|.::.|::|:.||
plant   500 EEEILVKQQAMDGRVDPNIAVQIHGLAKTYPGTTKLGCCKCTKTSPFHAVKGLWMNIAKDQLFCL 564

  Fly   889 LGRNGAGKSTLIKLLTG--------------QIRQSSGKVLLAGEHQVGVCWQDNILIPTLTARE 939
            ||.|||||:|.|..|||              .||.|.|...:  ...:|||.|.:||...|::.|
plant   565 LGPNGAGKTTTISCLTGINPVTGGDAKIYGNSIRSSVGMSNI--RKMIGVCPQFDILWDALSSEE 627

  Fly   940 HLQLYAQIK-IPPGGSGGVEEIRSEVAQTLQSLNFGKHESYPSWQLSGGYRRRLCVAIAFIASPS 1003
            ||.|:|.|| :||      ..|:|...:.|..:.........:...|||.:|||.||||.|..|.
plant   628 HLHLFASIKGLPP------SSIKSIAEKLLVDVKLTGSAKIRAGSYSGGMKRRLSVAIALIGDPK 686

  Fly  1004 VVILDEPCNGVDAKARKDIWQLIERLRQGRAVIFATHFMDEAKYLSDSLVIMRNGRIIAQHSRDS 1068
            :|.||||..|:|...|:.:|.:|:..::|||:|..||.|:||..|||.:.||..||:
plant   687 LVFLDEPTTGMDPITRRHVWDIIQESKKGRAIILTTHSMEEADILSDRIGIMAKGRL-------- 743

  Fly  1069 LQRLCTSNYSIRLRCADATG----VTFVIQKAQQLLPQTQVTHSGAAD-----YPHSLTI----- 1119
               .|... ||||:....||    |:|:..|           ..||.:     :...|.:
plant   744 ---RCIGT-SIRLKSRFGTGFVATVSFIENK-----------KDGAPEPLKRFFKERLKVEPTEE 793

  Fly  1120 NASYAEHLTPGAVE-----FLELLQSQVTAGSISDVELTTSSSLEQEFEQLNRNGE 1170
            |.::...:.|...|     |...||.:.:...|:|::|.. ::||:.|..:.|..|
plant   794 NKAFMTFVIPHDKEQLLKGFFAELQDRESEFGIADIQLGL-ATLEEVFLNIARRAE 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ldd	NP_001285513.1	rim_protein	179..1867	CDD:130324	178/771 (23%)
ABCA9	NP_001330984.1	rim_protein	<232..>857	CDD:130324	153/661 (23%)
		ABC_subfamily_A	520..753	CDD:213230	88/252 (35%)