Protein Alignment ldd and ABCA5

DIOPT Version :10

• Sequence 1: NP_001285513.1
• Gene: ldd / 318066
• FlyBaseID: FBgn0083956
• Length: 1998
• Species: Drosophila melanogaster
• Sequence 2: NP_001326002.1
• Gene: ABCA5 / 823930
• AraportID: AT3G47760
• Length: 936
• Species: Arabidopsis thaliana
• Alignment Length: 782
• Identity: 183/782 - (23%)
• Similarity: 310/782 - (39%)
• Gaps: 209/782 - (26%)

  Fly  1304 LNSWG----EYSERRYGGY---------------------GLNGSGATVWYNN--KG-------- 1333
            ||.|.    |.|...:.||                     .:|....|:|||:  ||
plant   230 LNLWRNNSIEISNEIFKGYRQGNLEEIINEVAAAYDLMDTDINNFNVTIWYNSTYKGDLRDRRVK 294

  Fly  1334 YHSMMAWLNDLNSELLRTTMNDSESSILTL--NEPWKLGFAELSTSSILRQAGDGSMVFILLIAF 1396
            |..:...:|.:::..|..........:...  ..|.:.....|..:|::   |.....:::|:.|
plant   295 YVRVPRSVNLVSNAYLEFLQGSGTKMLFDFVKEMPKQETRLRLEMASLI---GPIFFTWVILLLF 356

  Fly  1397 GLVVASGSVYLVNERVNGEKLQQRLCGVSAVTYWLVALVWDYLVMVLGLIVCLVVILMFGMPVFV 1461
            .:::.|    ||.|:....::..::.|:....||::...: :|.:.:..|:||::   ||
plant   357 PVMLTS----LVYEKQQHLRIIMKMHGLGDGPYWMITYAY-FLAISIVYIICLMI---FG----- 408

  Fly  1462 DRQQLVGIIGLSLAFSFACVPSVHVAEKIFSDSSIAIVSIF-CANLIVPLV-----------TMG 1514
                  ..|||..   |.           |:|.||..:..| |.||.:.:.           |..
plant   409 ------SAIGLKF---FR-----------FNDYSIQFIFYFLCINLQISIAFLVSSAFSKIETAS 453

  Fly  1515 IILILGVVGDGPAWDDWRHALNQAFLI--------FP-----IHALGDGFLELCKNYMVALVFRR 1566
            :...|.|.|.|         |..|||.        ||     |..|..||    ..|.....|.:
plant   454 VAAYLYVFGSG---------LLGAFLFQFLLEGLSFPRSWIYIMELYPGF----SLYRGLYEFSQ 505

  Fly  1567 YDIDSYKHPL--ASDLLGRHFTALLLVGVAALIINVLIEWHL---------------------LR 1608
            |   ::|..|  :..:..:.|....:..:..:||   :||.:                     |:
plant   506 Y---AFKRNLNGSGGMKWKDFNDSAMEEIFYIII---VEWFVALIAAYYTDKISSSGIDPFFFLK 564

  Fly  1609 R------------LWQRVERL------LDCTYRRELDKLGQLKLVNIQSIFKSCVDTGEAVRAEN 1655
            .            |.::|..:      ||..:.|.  |:.||.|.         ..||.|:..:|
plant   565 NQNPFKKSPSPYGLQRQVSAIAIEMEKLDVAHERV--KVEQLMLE---------TSTGHAIVCDN 618

  Fly  1656 LWLAY--RRGH---YAVRNVNFSVQRGECFGLLGKNGAGKSTIFKLLTGQLQPDVGQIYFE---- 1711
            |...|  |.|:   .|||.::.:|..|||||:||.|||||::...::||.::|..|..:..
plant   619 LKKVYPCRDGNPQKMAVRGLSLAVPSGECFGMLGPNGAGKTSFINMMTGLMKPTSGAAFVHGLDI 683

  Fly  1712 -------QPGISYCPQSNPLDPLLTTTECIRFYGRLRGIR--DLDQFLDRVLDTYEL--RPYKDV 1765
                   ...|..|||.:.|...||..|.:.|||||:.::  ||||.::..|.:..|  ....|.
plant   684 CKDMDIVYTSIGVCPQHDLLWETLTGREHLLFYGRLKNLKGSDLDQAVEESLKSVNLFRGGVADK 748

  Fly  1766 QVRNLSGGNRRKLTVAVTCCGCTPTVLMDEPTSDMDPVTRDMVYATIEQLLLARR--AVVLTSHS 1828
            .....|||.:|:|:||::..|....|.||||::.:||.:|..::..|::   |:.  |::||:||
plant   749 PAGKYSGGMKRRLSVAISLIGSPKVVYMDEPSTGLDPASRRSLWTAIKR---AKNHTAIILTTHS 810

  Fly  1829 VSEIEHLCQRVAVLRAGQVIASDSPQRLKSEHGGYYAVTCFCGPAQQAILSRSLNQRLPGARDLQ 1893
            :.|.|.||.|:.:...|::....:|:.||:.:||.|.:|.......:..:...:....|.|:.:.
plant   811 MEEAEFLCDRLGIFVDGRLQCVGNPKELKARYGGSYVLTMTTPSEHEKDVEMLVQDVSPNAKKIY 875

  Fly  1894 HYAHSLRFLV---RVRSPGSLGDAPLLSELFAILCDVCVN--VARFSLSRCRFETVFERILDSSE 1953
            |.|.:.:|.:   .||          :||:|..:.....|  |..:.|:....|.||.::..:::
plant   876 HIAGTQKFEIPKEEVR----------ISEVFQAVEKAKDNFRVFAWGLADTTLEDVFIKVARTAQ 930

  Fly  1954 SN 1955
            ::
plant   931 AS 932

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ldd	NP_001285513.1	rim_protein	179..1867	CDD:130324	166/687 (24%)
ABCA5	NP_001326002.1	rim_protein	<345..>936	CDD:130324	162/664 (24%)
		ABC_subfamily_A	618..839	CDD:213230	75/223 (34%)