Protein Alignment CG34120 and abca8

DIOPT Version :9

• Sequence 1: NP_001285513.1
• Gene: CG34120 / 318066
• FlyBaseID: FBgn0083956
• Length: 1998
• Species: Drosophila melanogaster
• Sequence 2: XP_031749971.1
• Gene: abca8 / 549630
• XenbaseID: XB-GENE-1005441
• Length: 1619
• Species: Xenopus tropicalis
• Alignment Length: 1515
• Identity: 368/1515 - (24%)
• Similarity: 626/1515 - (41%)
• Gaps: 317/1515 - (20%)

  Fly   633 VQVAYLLGLVVFVALSVRERIWMRESRNSMLMRSMGLKAHSELVAWALMSFLELCVIFALISGVL 697
            |.:.|||.|.:     .|||..|||     |::.|.||..:..::|.|: :|...:|.|.:..::
 Frog   235 VSLMYLLSLYI-----TRERREMRE-----LLKMMRLKDLAFWLSWGLL-YLFYILILANLMTLV 288

  Fly   698 YSGGILGYTNWFFMMFYCLSFGLCLISFCYMCTNFFNSANIGAVASALLFFISLCPFIIVLMFDA 762
            ....:...:::..:||..:.:|:.|:||.:|.:..|.|....|:|.   |||:|....:.|:...
 Frog   289 TKAFVFVQSSYGIIMFLFVFYGIALMSFTFMLSALFRSPRATAIAG---FFITLFLSALGLVLLR 350

  Fly   763 K---------LSVFESFLVDLSFTTAFAKGWGELIRMELQQEGLTVRHLIQVGPARSECAMALLM 818
            |         ||:|..|        |||.|..|.:.||...:|:   :...:....|....:.:.
 Frog   351 KDFPQALAVLLSIFPQF--------AFAVGLTESVHMESDLQGV---YFSDMAGDSSHVLSSFIS 404

  Fly   819 FLLDLLLYAVIGLAYQR--------------YKKTDNYSFVKVS----RSQLDGKL--------- 856
            ..||.:.|..:.|.:::              :.|:..:|..|:|    :::..|:.
 Frog   405 LALDSIFYMGLTLYFEKVLADKHGLKYEPFFFMKSSYWSKKKLSPVLTQTEDSGESSMGEFFERV 469

  Fly   857 -----GASLVNVSKLYGSKC-------AVSNLSLDFARNQVSCLLGRNGAGKSTLIKLLTGQIRQ 909
                 |...:.::|:....|       |:..|.|:....|::.|||.:||||:||:.:|:|....
 Frog   470 PIDLHGKEAIRINKVMKKYCDQDKNIEALRGLDLNIYEGQITALLGHSGAGKTTLLNILSGLCPA 534

  Fly   910 SSGKVLLAG------EH------QVGVCWQDNILIPTLTAREHLQLYAQIK-IPPGGSGGVEEIR 961
            |.|...:..      :|      :.|.|.|.::....||.:|:|.::|:|| ||.      ::|:
 Frog   535 SDGSATVYSYKLSDMQHLEEIKKRTGFCPQSDVKFNPLTVKENLTVFAKIKGIPR------KQIK 593

  Fly   962 SEVAQTLQSLNFGKHESYPSWQLSGGYRRRLCVAIAFIASPSVVILDEPCNGVDAKARKDIWQLI 1026
            .:|.:.|..|.....|:..:..||||.||:|.:.||.:..|.|::||||..|:|..:|..||.::
 Frog   594 HKVQKVLSDLQMNDIENVEADNLSGGQRRKLTLGIALLGDPQVLLLDEPTAGLDPCSRHHIWTIL 658

  Fly  1027 ERLRQGRAVIFATHFMDEAKYLSDSLVIMRNGRIIAQHSRDSLQRLCTSNYSIRLRCADATGVTF 1091
            :..:..|..:|:|.|||||..|:|...::.|||:....|...|:|.....|.:|::.:....|..
 Frog   659 KENKADRVTLFSTQFMDEADILADRKAVISNGRLKCVGSSLFLKRKWGIGYHLRMQVSPTCDVEL 723

  Fly  1092 VIQKAQQLLPQTQVTHSGAADYPHSLTINASYAEHLTPGAVEFLELLQSQVTAGSIS-DVELTTS 1155
            :....:|.:|..::|.....:..::|..     |::......||. |..||....:: .|.:||
 Frog   724 MTSIIKQHVPDAKLTAQNEEELTYTLPF-----ENMDAFPDLFLH-LDGQVGNSIVNYGVSMTT- 781

  Fly  1156 SSLEQEFEQLNRNGE----DAGPRRPAS----DRSGVVAGP----AMITD-------------EP 1195
              |:..|.:|...||    |.|...|.|    |:....||.    .:::|             :.
 Frog   782 --LDDVFLKLEGEGEIEKGDYGVFSPDSGAPEDKDCFSAGMEDSLLLMSDSGSATLSGLSLWRQQ 844

  Fly  1196 PTACKQFRLLMGKRLRHLSRNYR---LLLYVLLLP--------ALFELCAMWFVSYRLEDDFDTV 1249
            ..|..:.|||   :|:|.|:.:|   :||.:.::|        .:|.....|
 Frog   845 VLAIARVRLL---KLKHDSKTFRSILILLALFIIPIIMTTIVIKIFHKVITW------------- 893

  Fly  1250 LPLSRSLYPQTAQFLSHERATSFSEKLYPQLRTSC-DHLGECRVFNTSQQSYDWVLNSWGEYSER 1313
             .|:.|||.|..:...|...|..  ::|....:|. |.||..:..|.:.|    |:|  |||...
 Frog   894 -ELTPSLYFQHPEDRFHRYYTDL--QIYNNTGSSIEDFLGALKEQNIAVQ----VVN--GEYDME 949

  Fly  1314 R--YGG-----YGLNGSGATVWYNNKGYHSMMAWLNDLNSELLRTTMNDSESSILTLNEPWKLGF 1371
            .  |.|     ....|.|.|:..|.|..:::...:|.:::.||  .:.:|...|...|.|.....
 Frog   950 TTFYRGAIEVSQATKGYGFTIVGNPKAQNALPVLVNIISNALL--MIFNSTEHIRVWNHPVTEYL 1012

  Fly  1372 AELSTSSILRQAGDGSMVFILLIAFGLVVASGSVYLVNERVNGEKLQQRLCGVSAVTYWL----- 1431
            .| ...|:...:|    ..:||.|.||........:.:.|:.. :.|.|:.|:....||.
 Frog  1013 VE-DFESVTFYSG----FMLLLFASGLAPHFAMSSIEDRRIKA-RTQLRISGIFPSAYWFGQALV 1071

  Fly  1432 -VALVWDYLVMVLGLIVCL--VVILMFGMPVFVDRQQLVGIIGLSLAFSFACVPSVHVAEKIFSD 1493
             |.|.|..|.:::.::...  .||..| :|..:   .:.|:||    :..|.|..|:|...:|..
 Frog  1072 DVPLYWILLFLMVAILFSFNSQVIFSF-VPAII---LITGVIG----YGAAVVLYVYVISFVFGR 1128

  Fly  1494 --------SSIAIVSIFCANLIVPLVTMGII--LILGVVGDGPAWDDWRHALNQAFLIFPIHALG 1548
                    |...::|.|     :|::.:.::  ..:|:.               .||:.|...|
 Frog  1129 GKSHHDGWSIFFVISAF-----IPMILLDVVSTYAVGIT---------------FFLLLPASTL- 1172

  Fly  1549 DGFLELCKNYMVALVFRRYDIDSYKHPLASDLLGRHFTALLLVGVAALIINVLIEWHLLRRLWQR 1613
            .|.:. |             ||.| |...|.|...|...|....:..:|.:|:: | :|.|::..
 Frog  1173 SGIIR-C-------------IDVY-HFDRSTLEDEHLLYLFFPFLHIVIFSVIL-W-VLERVFGM 1220

  Fly  1614 VERLLDCTYRRELDK----LGQLKLVNIQSIFKSCVDTGEAVRAEN-----------------LW 1657
            .....:..||:::.|    ||:              ||.|.|.||.                 :.
 Frog  1221 RSLKTNLFYRKKVQKNQEELGE--------------DTDEEVLAERERVKMSSTTNNMEEKPIII 1271

  Fly  1658 LAYRRGHY---------------AVRNVNFSVQRGECFGLLGKNGAGKSTIFKLLTGQLQPDVGQ 1707
            :...|..|               |.:|::|.|::||..||||.|||||:|...:|.|:::|..|:
 Frog  1272 VDSLRKEYKVKKGKSFFKKNKKAATKNISFCVRKGEVLGLLGPNGAGKTTSIYMLAGEIRPTAGE 1336

  Fly  1708 I--------------YFEQPGISYCPQSNPLDPLLTTTECIRFYGRLRGI--RDLDQFLDRVLDT 1756
            :              |.....:.||||.|||.|.||..:.:..|..::|:  :|.:..:.||.:.
 Frog  1337 VLLCGTDPDKSQNSQYDPTGSLGYCPQDNPLWPNLTVKQHLEIYAAVKGLKKKDAETAIKRVSEA 1401

  Fly  1757 YELRPYKDVQVRNLSGGNRRKLTVAVTCCGCTPTVLMDEPTSDMDPVTRDMVYATIEQLLLAR-R 1820
            .||:.:.:...|.||.|..||:..|::..|....||:|||::.:||..:..::..|......: |
 Frog  1402 LELKEHLEKAARKLSAGVSRKVCFAISMLGNPNIVLLDEPSTGLDPKGQQRLWRAIRSAFRNKDR 1466

  Fly  1821 AVVLTSHSVSEIEHLCQRVAVLRAGQVIASDSPQRLKSEHG-GYYAVTCFCGPAQQAILSRSLNQ 1884
            ..:||:|.:.|.|.:|.|||::.:|::....|.|:|||:.| ||..........|...:...:.|
 Frog  1467 GAILTTHYMEEAEAVCDRVAIMVSGKLRCIGSIQQLKSKFGKGYLLEIKVKNSNQVDQIHNEIIQ 1531

  Fly  1885 RLPGARDLQHYAHSLRFLVRVRSPGSLGDAPL-LSELFAILCDVCVNVARFSLSRCRFETVFERI 1948
            ..|.|.....::..|.:.:.|.:..||..|.| |.|     .....|:..:|.|:.....||..:
 Frog  1532 IFPHAARQDRFSSLLVYKIPVENVQSLSKAFLDLEE-----AKRAYNIEEYSFSQPTLTQVFIEL 1591

  Fly  1949 LDSSESNGSNGVHKDQQQQV 1968
            ....|....:.....|.:|:
 Frog  1592 TKEQEREDFDSASTFQWKQL 1611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34120	NP_001285513.1	ABC2_membrane_3	<621..760	CDD:289468	36/126 (29%)
		ABC_subfamily_A	859..1073	CDD:213230	73/233 (31%)
		drrA	865..1162	CDD:130256	90/317 (28%)
		ABC2_membrane_3	1230..1601	CDD:289468	85/396 (21%)
		Mem_trans	1436..>1552	CDD:304621	24/127 (19%)
		ABC_subfamily_A	1651..1857	CDD:213230	72/254 (28%)
		drrA	1666..1945	CDD:130256	88/297 (30%)
abca8	XP_031749971.1	rim_protein	<225..1601	CDD:130324	366/1503 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010