Protein Alignment CG34120 and CG8908

DIOPT Version :9

• Sequence 1: NP_001285513.1
• Gene: CG34120 / 318066
• FlyBaseID: FBgn0083956
• Length: 1998
• Species: Drosophila melanogaster
• Sequence 2: NP_611464.3
• Gene: CG8908 / 37293
• FlyBaseID: FBgn0034493
• Length: 1626
• Species: Drosophila melanogaster
• Alignment Length: 1562
• Identity: 346/1562 - (22%)
• Similarity: 633/1562 - (40%)
• Gaps: 365/1562 - (23%)

  Fly   462 DLGIIKSKREEAGFAPEEDGPESGRSLSG--LFSIKQVENDTPDEDDDD----------FDLSLE 514
            ||..:.||    .||   ...|..::|.|  .:....:|.|....|.::          |.|.|.
  Fly    97 DLKAVGSK----AFA---SASELNKALIGKDTYGYVGIEFDDSFSDINELPINVTVGLRFPLHLR 154

  Fly   515 ESGDEKAAPKV---SASASDHEATTISPSSLDGVTTEE-------VRVTTEQTVVSGDPDLLLLK 569
            ::      ||:   :.|...|....:....::|....:       :|...|..|:   |:::|..
  Fly   155 KN------PKMVWDNTSILKHSKMDVDYYQVEGFLVVQAKLSEALIRAKNEAVVL---PEVILQH 210

  Fly   570 NEDVLKRSKRQGLFDLLGGFGGSGDANKKNKFEVDNMQFYTKQFPYPAFLNDVFKRG-LYLAQGV 633
            ..||.                           |||.:.            |.|...| |:|...:
  Fly   211 YPDVA---------------------------EVDRLD------------NRVALGGVLFLPVTI 236

  Fly   634 QVAYLLGLVVFVALSVRERIWMRESRNSMLMRSMGLKAHSELVAWALMSFLELCV--IFALISGV 696
            ..|||..::|     :..|..:|:     ::..||::|....::|.|::||.|.:  :|.::
  Fly   237 SAAYLAQMIV-----MERRDHLRD-----MLELMGVRAWIYWLSWFLVAFLLLSIPTVFMVL--- 288

  Fly   697 LYSGGILGYTNWFFMMFYCLSFGLCLISFCYMCTNFFNSANIGA-VASALLFFISLCPFIIVLMF 760
            |........::...::|:.|.:.|.:::..:|.::|| |..:|. ||..::..|...|:.::||.
  Fly   289 LLKWRYFSLSDSSLVLFFLLVYNLEVLTSAFMISSFF-SDTVGVQVAIVIVHLIGCLPWRLLLMG 352

  Fly   761 DAKLSVFESFLVDLSFTTAFAKGWGELIRMELQQEGLTVRHL---------IQVGPARSECAMAL 816
            ... ::..:..|.|...::.|.|..:.|:.|..:.||...:|         :.:||        :
  Fly   353 YVP-TLPRTIFVCLFLNSSLAMGLQQFIKSENLRLGLHWTYLFERTDWDEFVHLGP--------I 408

  Fly   817 LMFLLDLLLYAVIGLAY------------------------QRYKKTDNYSFVKVSRSQLDGKLG 857
            |:|:|...|..::.|||                        .|..::|::..    ..|..|..|
  Fly   409 LLFMLFGCLLRILVLAYMEQLRSYQNRKWYFPVQPSFWCRWNRRPRSDDFDV----EGQETGIRG 469

  Fly   858 ASLV----NVSKLYGSKCAVSNLSLDFARNQVSCLLGRNGAGKSTLIKLLTGQIRQSSGKVLLAG 918
            ..|:    |:.|::....||.:|:|:|.:::::..||.|.:||||::.||.|.:|.|:|::.:.|
  Fly   470 HPLIVRARNIEKVFNEWIAVKDLNLNFYQDEITVFLGHNDSGKSTILMLLAGFLRPSAGEITING 534

  Fly   919 ----------EHQVGVCWQDNILIPTLTAREHLQLYAQIKIPPGGSGGVEEIRSEV-AQTLQSLN 972
                      ...:.:|.|.|:|...:.||.|||.|.::|       |:.  |.|. |:|.:.|.
  Fly   535 YDLATNQRKARQSMCICPQPNVLFEKVNARWHLQFYCRLK-------GLN--RQEASAETDKYLE 590

  Fly   973 FGKHESYPSWQ---LSGGYRRRLCVAIAFIASPSVVILDEPCNGVDAKARKDIWQLIERLRQGRA 1034
            .|:.:.:.:.:   |..|.:|.|.:......:..:::||||...:|...|.::|.|:.|.|:||.
  Fly   591 IGRLQDFANTKVKNLPSGIKRMLMLCCNLCGNSKILLLDEPGTSMDPAMRSNMWDLLRRERKGRC 655

  Fly  1035 VIFATHFMDEAKYLSDSLVIMRNGRIIAQHSRDSLQRLCTSNYSIRLRCA--DATGVTFVIQKAQ 1097
            :|.|||.|:||:.::|.:|::.:.::|...:...|.::..:..|..|.|.  |...|..|....|
  Fly   656 IIMATHNMNEAEVVADQIVVLCDAQVIGYGTTGFLTQIAGTGSSYLLICTKMDTCIVAEVTNFLQ 720

  Fly  1098 QLLPQTQVTHSGAADYPHSLTINASY---AEHLTPGAVEFLELLQS---------QVTAGSISDV 1150
            ...|..:: |       :..:|..:|   .:::...|..||||.::         .|.|.::..|
  Fly   721 IRFPDIKL-H-------NEFSIYVTYELPTKYVQQYAALFLELEEALGELNLAEISVCAPTLGSV 777

  Fly  1151 ELTTSSSLEQEFEQLNRNGEDAGPRRPASDRSGVVAGPAMITDEPPTACKQFRLLMGKRLRHLSR 1215
            .|.....:.|.:.:::.....:.|....|..:.:........|.....|.|:|.::.|:.....|
  Fly   778 FLQMGEEMRQSWNRISSFDLLSSPSPMLSLLNLLPTFEVREDDGRVKCCNQWRAIVEKKRLFTLR 842

  Fly  1216 NYRLLLYVLLLPALFELCAMWF------VSYRLEDDFDTVLPLSRSLYPQTAQFLSHERATSFSE 1274
            :.:....::..|.:..|..:.|      |.:.|.:    :|....|:||:....:......:..|
  Fly   843 HQKFYCMIIATPIIICLLIISFSIFIFLVDHHLSE----LLVTDLSIYPKAVFVIDSPAEGNRFE 903

  Fly  1275 KLYPQLRTSCDHLGE-CRVFNTSQQSYDWVLNSWGEYSERRY-------GGYGLNGSGATVWYNN 1331
            :.|     ..:.:|: ..|.:||....|..|.:..|..:.:.       ..:..|.:....|.||
  Fly   904 RHY-----MANVIGQGGTVRSTSGTPIDDYLLAEMESDQVKVQHTFLAGATFDSNANSIIAWSNN 963

  Fly  1332 KGYH----SMMAWLNDLNSELLRTTMNDSESSILTLNEPWKLGFAELSTSSILRQAGDGSMVFIL 1392
            |..|    ||......:..||       ::..|..:|:|::         ..::||..| :::..
  Fly   964 KLKHGSALSMGLVYAAIGQEL-------AKLDIRIVNKPYQ---------DTVQQAVRG-LIYAS 1011

  Fly  1393 LIAFGLVV--------ASGSVYLVNERVNGEKLQQRLCGVSAVTYWLVALVWD---YLVMVLGLI 1446
            .|.|.::|        |..:|..:.||.:..:.||...|:|..||||..|.||   |:.|:|.||
  Fly  1012 TIEFAVLVFHYLVLGTAIFAVLPIVERRSKVQHQQFSSGMSRSTYWLSHLSWDYCFYIAMILPLI 1076

  Fly  1447 VCLVVILMFGMPVFVDRQQLVGIIGLSLAFSFACVPSVHVA-------EKIFSDSSIAIVSIFCA 1504
            |...:.:...:||.|   ||       |||.|:.:...::.       .|:||
  Fly  1077 VVAGITIGSVLPVIV---QL-------LAFGFSAISFTYLLCLMSNDFGKMFS------------ 1119

  Fly  1505 NLIVPLVTMGIILILGVVG-----DGPAWDDWRHA-LNQAFLIFPIHALGDGFLELCKNYMVALV 1563
                      |||.:.::|     ..|.....|:| :....|:.|.::|..|..|..:....:|
  Fly  1120 ----------IILYINMIGVLALFIHPKSPQTRYAVIESVLLVHPHYSLCCGMYEAIRMSTFSL- 1173

  Fly  1564 FRRYDIDSYKHPLASDLLGRHFTALLLVGVAALIINVLIEWHLLRRLWQRVERLLDCTYRRELDK 1628
                               :....|:..|.|.|.| |:..|         |.|.|:..:
  Fly  1174 -------------------KQLPYLIFSGAAYLTI-VVFAW---------VPRRLNYVF------ 1203

  Fly  1629 LGQLKLVNIQSIFKSCVDTGEAVRAENLWLAY-RRGHY------------------AVRNVNFSV 1674
                |.:..:.|:.|..|..:.|......||| ...||                  |||::...:
  Fly  1204 ----KSIRNEKIYPSYKDEDKEVDKMRRRLAYLTTAHYAFFPLILKNLSKRYGSFVAVRSLTLDL 1264

  Fly  1675 QRGECFGLLGKNGAGKSTIFKLLTGQLQPDVGQIYFE------QP-----GISYCPQSNPLDPLL 1728
            ...||.||||:||:|||:||:::.|.....||.|:.:      :|     .:.:||:...|...:
  Fly  1265 NPFECVGLLGRNGSGKSSIFRMIVGMESITVGSIHIKGYSLKTRPKDASRHVGFCPRELMLLSFM 1329

  Fly  1729 TTTECIRFYGRLRGIRD--LDQFLDRVLDTYELRPYKDVQVRNLSGGNRRKLTVAVTCCGCTPTV 1791
            |..:.:||...:.|||.  :...:..:.:.:||.|:.:.::...|.|.:|||.:|:..  ..|::
  Fly  1330 TGKDALRFCCLINGIRREYIKSLVASLAECFELVPHMNKRISTYSNGTKRKLMIAMGT--LAPSL 1392

  Fly  1792 L-MDEPTSDMDPVTRDMVYATIEQLLLARRAVVLTSHSVSEIEHLCQRVAVLRAGQVIASDSPQR 1855
            : :||||:.:|...:..:::.::.:....|:::||:|::.|.|.||..|.::..|.::...|..|
  Fly  1393 MCLDEPTAGVDMHAKYEIWSILDGIRQGGRSILLTTHNLEECEFLCTNVGIMDHGSLLCYGSLSR 1457

  Fly  1856 LK 1857
            ||
  Fly  1458 LK 1459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34120	NP_001285513.1	ABC2_membrane_3	<621..760	CDD:289468	33/142 (23%)
		ABC_subfamily_A	859..1073	CDD:213230	67/231 (29%)
		drrA	865..1162	CDD:130256	86/324 (27%)
		ABC2_membrane_3	1230..1601	CDD:289468	87/412 (21%)
		Mem_trans	1436..>1552	CDD:304621	31/131 (24%)
		ABC_subfamily_A	1651..1857	CDD:213230	63/238 (26%)
		drrA	1666..1945	CDD:130256	59/206 (29%)
CG8908	NP_611464.3	ABC2_membrane_3	69..394	CDD:289468	73/366 (20%)
		LivG	471..686	CDD:223488	66/223 (30%)
		ABC_subfamily_A	474..691	CDD:213230	65/225 (29%)
		ABC2_membrane_3	845..1192	CDD:289468	89/425 (21%)
		NatA	1242..1461	CDD:226927	59/220 (27%)
		ABC_subfamily_A	1242..1459	CDD:213230	57/218 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451216
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I138
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100045
Panther	1	1.100	-	-	P	PTHR19229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.900