Protein Alignment CG34120 and Eato

DIOPT Version :9

• Sequence 1: NP_001285513.1
• Gene: CG34120 / 318066
• FlyBaseID: FBgn0083956
• Length: 1998
• Species: Drosophila melanogaster
• Sequence 2: NP_001036360.1
• Gene: Eato / 34783
• FlyBaseID: FBgn0028539
• Length: 1597
• Species: Drosophila melanogaster
• Alignment Length: 1838
• Identity: 418/1838 - (22%)
• Similarity: 712/1838 - (38%)
• Gaps: 488/1838 - (26%)

  Fly   387 LHKRAYELNQNKLFLAALNLEDVGLKQASYRLHMDTDNTQPTFENRNRF-----------WFPG- 439
            |.|....|.:|.|.|..:.....|:..|  .||.   :.:|.....|:|           :|||
  Fly    13 LRKNLLYLQRNLLPLLLICSGFAGVLTA--YLHW---SVKPVLHQINQFEAKNEMVLRELYFPGN 72

  Fly   440 -----------PADSMVIDLKYHRGFVQLKQMVDLGIIKSKREEAGFAPEEDG------------ 481
                       |....::||          ..||||||..:     ..|..:.
  Fly    73 ELDYIYYSPISPNVEDIMDL----------LRVDLGIIPER-----LRPNNNSFEMQLEMEQQCR 122

  Fly   482 -----------PESGRSLSGLFSI----------KQVENDTPDE-----DDDDF----DLSLEES 516
                       |..|......:|:          |:..||  :|     ||||:    .|||:..
  Fly   123 GSCFAIDFHRVPNRGSDRKFRYSLSSNQMRISPRKRFVND--EEIYHQIDDDDYIRSGFLSLQHI 185

  Fly   517 GDEKAAPKVSASASDHEATTISPSSLDGVTTEEVRVTTEQTVVSGDPDLLLLKNEDV-LKRSKRQ 580
            .| |...|......|.|....|..:::.::.:..|:|...|:.|...:::||.:..| ....|:.
  Fly   186 LD-KQYMKYQELGKDFEVVVSSMPNMEVISMDSHRLTYFGTLCSILFNVVLLSSFVVPFVEEKQN 249

  Fly   581 GLFDLLGGFGGSGDANKKNKFEVDNMQFYTKQFPYPAFLNDVFKRGLYLAQGVQVAYLLGLVVFV 645
            ||.:                                 |||.|          ..:::|.||..|
  Fly   250 GLKE---------------------------------FLNLV----------TPMSFLNGLTFF- 270

  Fly   646 ALSVRERIWMRESRNSMLMRSMGLKAHSELVAWALMSFLELCVIFALISGVLYSGGILGYTNWFF 710
                             |:|         .|.:.|:      :||.|:...||..  ||...:.:
  Fly   271 -----------------LIR---------FVCYTLL------MIFVLVVAYLYKA--LGSICFAY 301

  Fly   711 MMFYCLSFGLCLISFCYMCTNFFNS---ANIGAVASALLFFISLCPFIIVLMFDAKLSVFESFLV 772
            :....|.:.|..:|:.|:.:..|:|   |.||.:|              :|:.....|...|:..
  Fly   302 VAVLFLLYILSTMSYAYLISICFHSVFYAKIGGLA--------------MLIIPYAFSFVRSWAT 352

  Fly   773 DLSF----TTAFAKGWGELIRMELQQE-----------GLTVRHLIQVGPARSECAMALLMF--L 820
            .|:|    |..|.:|      :::.|.           .:.|..:|:...:.......:|:|  .
  Fly   353 SLAFVCFSTNTFLEG------LDIFQTFSNKRKNREFGAVDVFRVIKSNSSTMFSVYVVLVFQSF 411

  Fly   821 LDLLLYAVIGLAY----------------QRYKKTDNYSFVKVSRSQLDGKLGASLVNVSKLYGS 869
            |..:||..:|..:                :.|.|.....:....|       |...:.:::|. .
  Fly   412 LYAMLYNYLGCVFPGPGGLKRPMFFFLDPKTYMKRQRNEYTTTPR-------GTHAIIITELC-K 468

  Fly   870 KCAVS--------NLSLDFARNQVSCLLGRNGAGKSTLIKLLTGQIRQSSGKVLLAGE------- 919
            |...|        ||::.....:::.|||.|||||:|::.::.|.:.:.|||:::..|
  Fly   469 KFQTSKRDTLISDNLNMTINNKEITVLLGHNGAGKTTMMNMIMGLVPKDSGKIIVCSERDVASYR 533

  Fly   920 HQVGVCWQDNILIPTLTAREHLQLYAQIKIPPGGSGGV-EEIRSEVAQTLQSL-------NFGKH 976
            |.:|.|.|.::.:..:|..:||:.:||::      |.. .:.|....:.|:.|       .|||:
  Fly   534 HLIGFCPQHSVFMSYMTCHQHLEFFAQLR------GACRSDARDWADEKLKKLGLSDKRNEFGKN 592

  Fly   977 ESYPSWQLSGGYRRRLCVAIAFIASPSVVILDEPCNGVDAKARKDIWQLIERLRQGRAVIFATHF 1041
                   ||||.:|||.:.||...:..:||||||.:|:|..:|:::|.::..||:.:||:..||:
  Fly   593 -------LSGGMKRRLSLGIAIAGNTKIVILDEPSSGLDINSRRELWDILLNLRKEKAVLVTTHY 650

  Fly  1042 MDEAKYLSDSLVIMRNGRIIAQHSRDSLQRLCTSNYSIRLRCADATG-VTFVIQKAQQLLPQTQV 1105
            |:||:.|.|::.|:.||::.:..|...|:|.....|.::|...|.|. ...:::.....:|..:|
  Fly   651 MEEAEVLGDTICILANGKLQSIGSPLELKRKSGIGYRLKLEINDFTSREVEIMEIIHHFVPTARV 715

  Fly  1106 THSGAADYPHSLTINASYAEHLTPGA-----VEFLELLQSQVTAGSISDVELTTSSSLEQEFEQL 1165
            .:          .:|.:....| |.|     .:.|..|:::.....|..:.: |.:|||..|  |
  Fly   716 LN----------VVNPTVYICL-PYAYKNCFAQMLYRLETESKELGIHTISM-TDTSLEDVF--L 766

  Fly  1166 NRNGEDAGPRRPASDRSG--VVAGPAMITDEPPTACKQFRLLMG---KRLRHLSRNYRLLLYVLL 1225
            ...||......|...|:.  ::|....:.|.||.. ..|:|.|.   |:...:|..:...|.:|.
  Fly   767 RCAGEQDQVDTPDGSRNDAPLLAHYKRLQDHPPHR-GLFQLWMAVFYKKWTFISNEWLYTLIMLC 830

  Fly  1226 LP------ALFELCAMWFVSYRLEDDFDTVLPLSRSLYPQTAQFLSHERATSFSEKLYPQLRTSC 1284
            :|      |:..:.||..|      :.:..|||..|.......::  ...|.....|..|||...
  Fly   831 IPFVCVFGAILVMHAMSLV------ENEEALPLKLSQMGSGVIYV--HNPTGHHAHLEQQLRQQI 887

  Fly  1285 D---------HL-GECRVFNTSQQSYDWVLNSWGEYSER------RYGGYGLNGSGAT------V 1327
            :         || |...|.|   :|.|...::..::.|:      .|||    |.|.:      :
  Fly   888 ELNGITAKTMHLRGSNDVKN---ESLDLQRDNLADFLEQVIGIIDMYGG----GRGTSDTPTIEI 945

  Fly  1328 WYNNKGYHSMMAWLNDLNSELLRTTMNDSESSILTLNEPWKLGFAELSTSSILRQAGDGSMVFIL 1392
            :|:...|||.:..:|.::|.:|:  :...||.|.|...|.:...:::|.|.
  Fly   946 FYSGNRYHSSVELINLVDSAMLK--LGRPESEIDTTYVPIRRFVSDISPSR-------------- 994

  Fly  1393 LIAFGLVVASGSVYLV--------NERVNGEKLQQRLCGVSAVTYWLVALVWDYLVMVLGLIVCL 1449
            |..:.::|..|..:.:        .|..||.|..|.:   |..|||.....:|.|:::   .||:
  Fly   995 LEYYAVIVPIGMFFFMFYFISLPFREYANGFKQLQTM---SRFTYWFAHFTFDMLILI---FVCV 1053

  Fly  1450 VVI----LMFGMPVFVDRQQLVGIIGLSLAFSFAC--VPSVHVAEKIFSDSSIAIVSIF-----C 1503
            .:.    ||....::...:  :.:|.||: |.:.|  :|.::.....|  .||:.:|.:     .
  Fly  1054 ALFSLQSLMMPSELYTTAE--LKVIVLSI-FFYGCSYLPILYALGNNF--KSISTISTYLLLMLI 1113

  Fly  1504 ANLIVPLVTMGIILILGVVGDGPAWDDWRHALNQAFLIF-PIHALGDGFLELCKNYMVALVFRRY 1567
            .:.|.||:|......:.:           |....|||.| |...|...|..:.:|::
  Fly  1114 VSAIAPLITSSNAAAMKL-----------HETKIAFLCFLPDFNLNHQFRIINENFI-------- 1159

  Fly  1568 DIDSYKHP------LASDLLGRHFTALLLVGVAAL-IINVLIEWHLLRR-----LWQRVERLLDC 1620
               :.:||      ::.|....:.||   |||..: ...:::|...|||     :|:...:
  Fly  1160 ---TRRHPALIKGLISQDTFFAYATA---VGVMVMAFFTIVLEHKYLRRRIHDGIWEWAFQ---- 1214

  Fly  1621 TYRRELDKLGQLKLVNIQSIFKSCVDTGEAV--------RAENLWLAYRRGHY----AVRNVNFS 1673
              |::.:..|.|....|..| ..|....:.|        ...:|.:...|..|    ||..|:|:
  Fly  1215 --RKKYNSTGTLPSTPISEI-DDCAREEKRVTDLIKDPLNDHSLIVHNLRKRYGDKLAVDGVSFA 1276

  Fly  1674 VQRGECFGLLGKNGAGKSTIFKLLTGQLQPDVGQIYFEQPGI-----------SYCPQSNPLDPL 1727
            ..:||||||||.|||||::.|:::...|..|.|.|..:...|           .||||.:.|:..
  Fly  1277 AAQGECFGLLGVNGAGKTSTFQMIAANLPLDGGTIRIKGADIREHELKYREYFGYCPQYDALNKF 1341

  Fly  1728 LTTTECIRFYGRLRGI--RDLD------QFLDRVLDTYELRPYKDVQVRNLSGGNRRKLTVAVTC 1784
            :|..:|:.:...|||:  |..|      :.:...|:...|..|:.||||:.|||.:|||..|:..
  Fly  1342 MTAEQCLYYMALLRGLSRRRTDGPASCKEHVKYWLEKMHLTKYQKVQVRHYSGGTKRKLLAAMAM 1406

  Fly  1785 CGCTPTVLMDEPTSDMDPVTRDMVYATIEQLLLARRAVVLTSHSVSEIEHLCQRVAVLRAGQVIA 1849
            .|....||:||||:.:||::|..::..|:......|.|||||||:.|.|.||.|:|::..|:...
  Fly  1407 IGAPALVLLDEPTTGVDPISRRFLWQCIKDFQGKDRTVVLTSHSMDECEELCNRLAIMAHGKFKC 1471

  Fly  1850 SDSPQRLKSEHGGYYAVTCFCGPAQQ---AILSRSLNQRLPGARDLQHYAHSLRFLVRVRSPGSL 1911
            .::...||...|....:........:   :.::.:|....||....:.:|.:|.:.|..:.
  Fly  1472 LNNICALKRLSGFTIKLKMKADTETEMNVSTITGTLKSEFPGLELRESHAGTLTYFVSTQE---- 1532

  Fly  1912 GDAPLLSELFAI----LCD-VCVNVARFSLSRCRFETVFERILDSSESNGSNGVHKDQQQQVAKN 1971
             ...|.|.:|.|    |.| :...||.:|::.|..|.:|.:.                 ::.||:
  Fly  1533 -SVVLWSSVFKIAEEYLGDRLSALVADYSVNECTLEDIFLKF-----------------EREAKS 1579

  Fly  1972 DLPSKSPAVGGTLETGYI 1989
            ...|:..:|....|..|:
  Fly  1580 QSTSRQTSVQRRPECSYV 1597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34120	NP_001285513.1	ABC2_membrane_3	<621..760	CDD:289468	27/141 (19%)
		ABC_subfamily_A	859..1073	CDD:213230	71/236 (30%)
		drrA	865..1162	CDD:130256	88/325 (27%)
		ABC2_membrane_3	1230..1601	CDD:289468	88/419 (21%)
		Mem_trans	1436..>1552	CDD:304621	27/127 (21%)
		ABC_subfamily_A	1651..1857	CDD:213230	79/236 (33%)
		drrA	1666..1945	CDD:130256	95/305 (31%)
Eato	NP_001036360.1	ABC2_membrane_3	<209..347	CDD:289468	41/229 (18%)
		CcmA	460..767	CDD:224054	89/334 (27%)
		ABC_subfamily_A	461..679	CDD:213230	69/231 (30%)
		ABC2_membrane_3	<937..1117	CDD:289468	42/206 (20%)
		ABC_subfamily_A	1255..1479	CDD:213230	78/223 (35%)
		drrA	1262..1573	CDD:130256	97/315 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451217
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I138
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	1	1.000	-	-		otm46598
orthoMCL	1	0.900	-	-		OOG6_100045
Panther	1	1.100	-	-	P	PTHR19229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.800