DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stg1 and cacng2b

DIOPT Version :9

Sequence 1:	NP_001027082.1	Gene:	stg1 / 318064	FlyBaseID:	FBgn0064123	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_001186659.1	Gene:	cacng2b / 569855	ZFINID:	ZDB-GENE-090624-3	Length:	321	Species:	Danio rerio

Alignment Length:	233	Identity:	64/233 - (27%)
Similarity:	100/233 - (42%)	Gaps:	55/233 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 GYLWLITPVAASISVAIVIAALAGPQWLFTEE--KLPNANYNGTA--NFKALDDGAYITKYTKSS 283
            |...|:|.|.|..:.:::..|:....||::..  |:.:.|.|.|:  |.:.:         |.|.
Zfish     7 GVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKIKSTNENETSKKNEEVM---------THSG 62

  Fly   284 LWILCT---TLPGLDADSYNCVKIDYFSNEG-YQPDPHDSTAAIPYTVTKSCPIFL----AAGVF 340
            ||..|.   ...|:      |.:||:|..:. |:.|..:              .||    |:.:|
Zfish    63 LWRTCCLEGNFKGM------CKQIDHFPEDADYEADASE--------------YFLRAVRASSIF 107

  Fly   341 LVISFI-VFLIPTCSHQNNLY------YFSAGILFIVSGLVMLIGLIAYISILKAEIGSKLRPRS 398
            .::|.| :|:...|...:..|      ..||||.|:.:||..:||:|.|||   |..|...:..|
Zfish   108 PILSVILLFMGGLCVAASEFYKSRHNIILSAGIFFVSAGLSNIIGIIVYIS---ANAGDPSKSDS 169

  Fly   399 TLQPALIKVSYGQSFFLFVFGFIVTEFVGVLNIFLFIN 436
            ...    ..|||.||:.....||:.|.||||.:.:||:
Zfish   170 KKN----SYSYGWSFYFGALSFIMAEMVGVLAVHMFID 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stg1	NP_001027082.1	PMP22_Claudin	235..429	CDD:304458	55/212 (26%)
cacng2b	NP_001186659.1	PMP22_Claudin	6..197	CDD:250157	61/225 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9896
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000345
OrthoInspector	1	1.000	-	-		otm24542
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12107
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.010