Protein Alignment stg1 and Cacng8

DIOPT Version :10

• Sequence 1: NP_001400987.1
• Gene: stg1 / 318064
• FlyBaseID: FBgn0288700
• Length: 1000
• Species: Drosophila melanogaster
• Sequence 2: NP_542427.1
• Gene: Cacng8 / 140729
• RGDID: 628808
• Length: 421
• Species: Rattus norvegicus
• Alignment Length: 509
• Identity: 127/509 - (24%)
• Similarity: 189/509 - (37%)
• Gaps: 166/509 - (32%)

  Fly   225 LW-------LITPVAASISVAIVIAALAGPQWLFTEEKLPNANYNGTANFKALDD--------GA 274
            ||       |:|.:.|..:..::..|::...||:|...:.|     |.|..|.||        |:
  Rat    13 LWCEKGVQVLLTTIGAFAAFGLMTIAISTDYWLYTRALICN-----TTNLTAGDDGPPHRGGSGS 72

  Fly   275 YITK----YTKSSLWILCTTLPGLDADSYNCVKIDYFSNE-GYQPDPHDSTAAIPYTVTKSCPIF 334
            ...|    .|.|.||.:| .|.||....  ||||::|..: .|.   |||...:...|.
  Rat    73 SEKKDPGGLTHSGLWRIC-CLEGLKRGV--CVKINHFPEDTDYD---HDSAEYLLRVVR------ 125

  Fly   335 LAAGVFLVISFIVFLI-PTCSHQNNLY------YFSAGILFIVSGLVMLIGLIAYISILKAEIGS 392
             |:.:|.::|.|:.|: ..|...:.:|      ...|||||:.:||..:||:|.|||....|.|.
  Rat   126 -ASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGP 189

  Fly   393 KLRPRSTLQPALIKVSYGQSFFLFVFGFIVTEFVGVLNIFLFINLQEVSYYSRLPCFSVANIHAK 457
            |........     .|||.||:.....||:.|.:|||.:.::|.....::     |.|.:::
  Rat   190 KRDEEKKNH-----YSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAH-----CQSRSDL--- 241

  Fly   458 LKE--------GQHPLS----DSYK-RYKQPGITTASQEGLSSA---------GQGQQGHQSHHP 500
            ||.        |..|.:    .||: ||::.  :.:|..|.|.|         |.|..|..|...
  Rat   242 LKAGGGAGGSGGSGPSAILRLPSYRFRYRRR--SRSSSRGSSEASPSRDASPGGPGGPGFASTDI 304

  Fly   501 THQPHPTAQPPHGILRSGNSRLHQVYDAGRG--------HPGMTGQIGHSGQTQTLPGACRKHPN 557
            :... .:..|..|.:.:|      :..||.|        :.|..|..|..|     .|:.|   :
  Rat   305 SMYT-LSRDPSKGSVAAG------LASAGGGGGGAGVGAYGGAAGAAGGGG-----TGSER---D 354

  Fly   558 AGSNLN-LYLHNDLERRFYFEKPAVSKCNLHSRSFAKSLNELCTDTSVSSTHVPAPLLPSAADPL 621
            .||:.. |.|||                     :|.|   |..:..:|:.|..||         .
  Rat   355 RGSSAGFLTLHN---------------------AFPK---EAASGVTVTVTGPPA---------A 386

  Fly   622 PAPALFADLPQEFPLTRSVSTATEIYPASSSAPAPPSAQMKRKQQRNMATNTNT 675
            ||||                      |.:.:||||.:.     .:...|:||||
  Rat   387 PAPA----------------------PPAPAAPAPGTL-----SKEAAASNTNT 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stg1	NP_001400987.1	PMP22_Claudin	235..429	CDD:473919	62/213 (29%)
Cacng8	NP_542427.1	PMP22_Claudin	17..222	CDD:473919	66/227 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	271..304		8/34 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	342..363		7/28 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..421		18/72 (25%)