DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stg1 and cacng4

DIOPT Version :9

Sequence 1:	NP_001027082.1	Gene:	stg1 / 318064	FlyBaseID:	FBgn0064123	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	XP_031750551.1	Gene:	cacng4 / 100486554	XenbaseID:	XB-GENE-1014199	Length:	328	Species:	Xenopus tropicalis

Alignment Length:	229	Identity:	70/229 - (30%)
Similarity:	105/229 - (45%)	Gaps:	43/229 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 GYLWLITPVAASISVAIVIAALAGPQWLFTEEKLPNANYNGTANFKALDDGAYITKYTK-----S 282
            |...|:..|.|..:.:::..|:....||::...:    .||| |. ..||.....|.||     |
Frog     7 GVQMLLATVGAFAAFSLMSIAIGTDYWLYSRAHI----CNGT-NI-TQDDAQAQPKKTKGDLTHS 65

  Fly   283 SLWILCTTLPGLDADSY--NCVKIDYFSNEG-YQPDPHDSTAAIPYTVTKSCPIFLAAGVFLVIS 344
            .||.:| .:.||    |  ||.:|::|..:. |.   |||:..:       ..|..|:.||.::|
Frog    66 GLWRIC-CIEGL----YKGNCFRINHFPEDNDYD---HDSSEYL-------LRIVRASSVFPILS 115

  Fly   345 FIVFLI-PTC-------SHQNNLYYFSAGILFIVSGLVMLIGLIAYISILKAEIGSKLRPRSTLQ 401
            .|:.|: ..|       |.:||: ..||||||:.:||..:||:|.|||....:...|.......|
Frog   116 AILLLLGGLCIGAGRLYSRRNNI-ILSAGILFVAAGLSNIIGIIVYISSNAGDPSDKKDEDKKNQ 179

  Fly   402 PALIKVSYGQSFFLFVFGFIVTEFVGVLNIFLFI 435
                 .:||.||:.....|||.|.:|||.:.::|
Frog   180 -----YNYGWSFYFGALSFIVAETIGVLAVNIYI 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stg1	NP_001027082.1	PMP22_Claudin	235..429	CDD:304458	63/209 (30%)
cacng4	XP_031750551.1	PMP22_Claudin	6..203	CDD:419754	68/222 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I10462
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000345
OrthoInspector	1	1.000	-	-		otm48588
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000