DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stg1 and tmem235b

DIOPT Version :9

Sequence 1:	NP_001027082.1	Gene:	stg1 / 318064	FlyBaseID:	FBgn0064123	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	XP_001919554.1	Gene:	tmem235b / 100150722	ZFINID:	ZDB-GENE-130603-43	Length:	200	Species:	Danio rerio

Alignment Length:	225	Identity:	46/225 - (20%)
Similarity:	80/225 - (35%)	Gaps:	35/225 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 GYLWLITPVAASISVAIVIAALAGPQWLFTEEKLPNANYNGTANFKALDDGAYITKYTKSSLWIL 287
            |::.:...:...:|.:.:..|:....|...|::..|......:|               |.||
Zfish     6 GFVVVCGGLTGVLSFSCLALAIGTEYWYIIEDQRTNHTNPERSN---------------SGLW-- 53

  Fly   288 CTTLPGLDAD-SYNCVKIDYFSNEGYQPDPHDSTAAIPYTVTKSCPIFLAAGVFLVISFIVFLIP 351
                 |:..| ..|.....|..:|......|...|.:       .|:.|   |.||...|..|:.
Zfish    54 -----GVTEDEKSNSEDTGYSESERQMEIMHCVIAIL-------LPLSL---VMLVFGGICGLVS 103

  Fly   352 TCSHQNNLYYFSAGILFIVSGLVMLIGLIAYISILKAEIGSKLRPRSTLQPALIKVSYGQSFFLF 416
            :.:....|...||. .|::..|:.|.|:..||...:..:....|.....|.|.:..|:|.|..:.
Zfish   104 SLARSRALLIGSAS-YFLLCSLLTLSGVSLYIRYSQKALEETERRMGREQMAQVHTSFGWSMGMA 167

  Fly   417 VFGFIVTEFVGVLNIFLFINLQEVSYYSVS 446
            ...|::....|:| :.|.:.|..::.|..|
Zfish   168 WISFLLEVMTGLL-LLLAVKLVPLTQYEDS 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stg1	NP_001027082.1	PMP22_Claudin	235..429	CDD:304458	40/194 (21%)
tmem235b	XP_001919554.1	PMP22_Claudin	17..178	CDD:304458	39/193 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	2	1.870