DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stg1 and cacng2

DIOPT Version :9

Sequence 1:	NP_001027082.1	Gene:	stg1 / 318064	FlyBaseID:	FBgn0064123	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_001096418.1	Gene:	cacng2 / 100125024	XenbaseID:	XB-GENE-965516	Length:	321	Species:	Xenopus tropicalis

Alignment Length:	233	Identity:	62/233 - (26%)
Similarity:	96/233 - (41%)	Gaps:	55/233 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 GYLWLITPVAASISVAIVIAALAGPQWLFTEEKLPNANYNGTANFKALDDGAYITK----YTKSS 283
            |...|:|.|.|..:.:::..|:....||::         .|....|::.:.....|    .|.|.
Frog     7 GVQMLLTTVGAFAAFSLMTIAVGTDYWLYS---------RGVCKSKSISENETSKKNEEVMTHSG 62

  Fly   284 LWILCT---TLPGLDADSYNCVKIDYFSNEG-YQPDPHDSTAAIPYTVTKSCPIFL----AAGVF 340
            ||..|.   ...|:      |.:||:|..:. |:.|              :...||    |:.:|
Frog    63 LWRTCCLEGNFKGV------CKQIDHFPEDADYEAD--------------TAEYFLRAVRASSIF 107

  Fly   341 LVISFI-VFLIPTCSHQNNLY------YFSAGILFIVSGLVMLIGLIAYISILKAEIGSKLRPRS 398
            .::|.| :|:...|...:..|      ..||||.|:.:||..:||:|.|||   |..|...:..|
Frog   108 PILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYIS---ANAGDPSKSDS 169

  Fly   399 TLQPALIKVSYGQSFFLFVFGFIVTEFVGVLNIFLFIN 436
            ...    ..|||.||:.....||:.|.||||.:.:||:
Frog   170 KKN----SYSYGWSFYFGALSFIIAEMVGVLAVHMFID 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stg1	NP_001027082.1	PMP22_Claudin	235..429	CDD:304458	53/212 (25%)
cacng2	NP_001096418.1	PMP22_Claudin	6..197	CDD:334271	59/225 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I10462
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000345
OrthoInspector	1	1.000	-	-		otm48588
Panther	1	1.100	-	-	O	PTHR12107
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.010