DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tbc and MSB3

DIOPT Version :10

Sequence 1:NP_608395.6 Gene:tbc / 318059 FlyBaseID:FBgn0052506 Length:1155 Species:Drosophila melanogaster
Sequence 2:NP_014106.1 Gene:MSB3 / 855423 SGDID:S000005237 Length:633 Species:Saccharomyces cerevisiae


Alignment Length:508 Identity:97/508 - (19%)
Similarity:165/508 - (32%) Gaps:164/508 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   723 LEFDEQQQQQQQQAECAVS----GNHLTVKPIPRAMKTSTDSGHVDESFNELDEPDEEDNKQKQQ 783
            ::.|:|:...|.:...|..    |...|||  ..::....|..|.|.|                .
Yeast     1 MQNDQQRFSLQNRTVLAHPYKRLGGAFTVK--SPSVPNFHDKMHSDHS----------------S 47

  Fly   784 QDEKISESESKLPDYRKLEEQINQEPSCSASTASSYETVG-----------------PGEVHQRP 831
            .|..:.....:..|:|.:      |||| ...||..|..|                 .||.....
Yeast    48 SDSALVNGSFRANDHRSV------EPSC-LGQASPSEHDGNLSVIDLYGDEVESQRAEGEDDDDN 105

  Fly   832 NSDTRSVLSPEYLSADDLQL-PDDEDAVRPPPPPAAAAVIITKASVDITNWERSPKAAEGDQMSP 895
            |.|..:. ..|.:.:|||.| |||::..|.....||:|.......::.|:::|.....:.:.:|.
Yeast   106 NGDNGNE-DLEEVHSDDLDLVPDDDNRQRVELEGAASATSANSNGINNTHFDRYGFKKQNNYISE 169

  Fly   896 LE-------------------EQAGESGGAGVNMDALQQPKSAC---------ASPA-------- 924
            .|                   :...|..|..|..|:..:..|..         ..||        
Yeast   170 AEYDKWWVEYSQYCVRRKHKWQLLLEKSGLPVTDDSPSRFPSKSERLKRYVRKGIPAEWRGNAWW 234

  Fly   925 ---------SSNGGVYSSELL------------EQFGLNLHRIEKDVQRCDRNYWYFANENLDK- 967
                     :.|.||| |:||            |:...:|..||:|:.|...:..:|.:...:| 
Yeast   235 HFARGQEKLNKNKGVY-SQLLRKMKQIKKQNPNEKQVQDLDIIERDLNRTFPDNIHFQSSLHNKE 298

  Fly   968 -------LRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMIE------- 1018
                   ||.|:..:...:..:||.|.| :.:|.||::|.||..::.....:..|.:.       
Yeast   299 GPPIIKSLRRVLVAFSLYNPKIGYCQSM-NFLAGLLLLFLDEERAFWMLVIITSRYLPGVHNINL 362

  Fly  1019 ---NFPSGGAM------------------DMHFANMRSLIQILDSEMYDLMDSNGDYTHFYFCYR 1062
               |...|..|                  |.|..|.::........::::..:.       |.||
Yeast   363 EGVNIDQGVLMLCVKEYIPEVWSYIKPSIDHHQKNNKTFSPSNKKVLFNMQKNE-------FLYR 420

  Fly  1063 ----------WFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVLFLALALLE 1105
                      ||:..|...:..:.....|:.::    ....||:..::||:|:
Yeast   421 LPPITLCTASWFMSCFVGVVPIETTLRIWDCLF----YEESHFLFKVSLAVLK 469

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tbcNP_608395.6 RUN_SGSM1_like 21..214 CDD:439049
PH_RUTBC 292..466 CDD:275431
TBC 923..1087 CDD:214540 44/238 (18%)
MSB3NP_014106.1 COG5210 15..540 CDD:227535 94/494 (19%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.