DRSC/TRiP Functional Genomics Resources

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Protein Alignment tbc and BUB2

DIOPT Version :10

Sequence 1:NP_608395.6 Gene:tbc / 318059 FlyBaseID:FBgn0052506 Length:1155 Species:Drosophila melanogaster
Sequence 2:NP_013771.1 Gene:BUB2 / 855077 SGDID:S000004659 Length:306 Species:Saccharomyces cerevisiae


Alignment Length:227 Identity:48/227 - (21%)
Similarity:92/227 - (40%) Gaps:41/227 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   945 RIEKDVQR---CDRNYWYFANENLDKLRNVISTYVWE-----------HLDVG-YMQGMCDLVAP 994
            :|:.|..|   .|.|:....:|  |.|...:|.:.|:           .:.|. |:|||..|:||
Yeast    78 KIKNDTSRTFQTDPNFRNRVSE--DALIRCLSCFAWQTQQRRQKTRFGRIPVSTYVQGMNVLLAP 140

  Fly   995 LLVIFDDESLSYSCFCKLMERMIE-------NFPSGGAMDMHFANMRSLIQILDSEMYDLMDSNG 1052
            ||.....|.::|..|.||...||.       |....||..:..:     ::|:|.::...:..|.
Yeast   141 LLYSCPSEPMAYQLFTKLCYEMIPTYLTKNLNGAQNGAKLLDIS-----LRIIDPKLSKFLSDNL 200

  Fly  1053 DYTHFYFCYRWFLLDFKRELVYDDVFATWEVIWA-AKHIASGHFVLFLALALLETYRDIILSNSM 1116
            .....|.......|....:.: |.|...|:.::| ..|:.    :||:...|::....:..|:|.
Yeast   201 LTAEIYGMPSILTLSSCNKPL-DQVIKLWDFMFAYGFHMN----ILFVVAFLVKMRSKVFKSDSP 260

  Fly  1117 DFTDVIKFFNEMAERHNAQSVLQLARSLVLQL 1148
              .::::.|.:.    :|..:::|....:.::
Yeast   261 --VNLLRQFPDF----DADEIIRLGVGFIAKI 286

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tbcNP_608395.6 RUN_SGSM1_like 21..214 CDD:439049
PH_RUTBC 292..466 CDD:275431
TBC 923..1087 CDD:214540 39/164 (24%)
BUB2NP_013771.1 COG5210 <1..304 CDD:227535 48/227 (21%)
Blue background indicates that the domain is not in the aligned region.

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