DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbc and AT5G54780

DIOPT Version :9

Sequence 1:	NP_001285494.1	Gene:	tbc / 318059	FlyBaseID:	FBgn0052506	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	NP_200289.2	Gene:	AT5G54780 / 835568	AraportID:	AT5G54780	Length:	432	Species:	Arabidopsis thaliana

Alignment Length:	610	Identity:	109/610 - (17%)
Similarity:	192/610 - (31%)	Gaps:	276/610 - (45%)

- Green bases have known domain annotations that are detailed below.

  Fly   589 LTKERWQ-LLNVNGVLENATEFYRLVYFGGVQPELRQEVWPYLLGHYAFGSTTEDRKKQDETCKH 652
            |:..:|| .....|.|:......| :..||:.|.:|.|||.:|||.|...||.|:|::
plant    35 LSVRKWQAAFTTEGFLDIGKTLSR-IQRGGIHPSIRGEVWEFLLGCYDPKSTFEEREQ------- 91

  Fly   653 YYETTMSEWLAVDAIVQQREKEKTARAVAKLSSGSNSGNDRTVRAADLEAGGDLENEVFEDISDI 717
                           ::||.:
plant    92 ---------------IRQRRR-------------------------------------------- 97

  Fly   718 SDPGDLEFDEQQQQQQQQAECAVSGNHLTVKPIPRAMKTSTDSGHVDESFNELDEPDEEDNKQKQ 782
                 |::...:::.:|......||..:|...|       |:.|.
plant    98 -----LQYASWKEECKQMFPVIGSGGFITAPVI-------TNKGE-------------------- 130

  Fly   783 QQDEKISESESKLPDYRKLEEQINQEPSCSASTASSYETVGPGEVHQRPNSDTRSVLSPEYLSAD 847
                         |.|..:   :.||.:..|:.:..::
plant   131 -------------PIYDPI---VLQETNLGANGSDFFK--------------------------- 152

  Fly   848 DLQLPDDEDAVRPPPPPAAAAVIITKASVDITNWERSPKAAEGDQMSPLEEQAGESGGAGVNMDA 912
            ||                                     |:.|    ||:::
plant   153 DL-------------------------------------ASRG----PLDQK------------- 163

  Fly   913 LQQPKSACASPASSNGGVYSSELLEQFGLNLHRIEKDVQRCDRN-YWYFANENLDKLRNVISTYV 976
                                   :.|:.|.||:|..||.|.||. .:|...|||.||.::::.|.
plant   164 -----------------------VIQWLLTLHQIGLDVNRTDRTLVFYEKKENLSKLWDILALYA 205

  Fly   977 WEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMIENFPSGG---AMDMHFANMRSLIQ 1038
            |...||||.|||.||.:|::::.:||:.::.||.:||.|:..||...|   .::....::.|:.|
plant   206 WIDNDVGYCQGMSDLCSPMIMLLEDEADAFWCFERLMRRLRGNFRDTGRSVGVEAQLTHLASITQ 270

  Fly  1039 ILDSEMYDLMD--SNGDYTHFYFCYRWFLLDFKRELVYDDVFATWEVIWAAKH------------ 1089
            |:|.:::..::  ..|||   .|..|..::.|:||..:.|....||::||.::
plant   271 IIDPKLHHHLEKLGGGDY---LFAIRMIMVQFRREFSFCDSLYLWEMMWALEYDPEMYSLYEEPQ 332

  Fly  1090 ---------------------------------IASGHFVL--FLALALLETYRDIILSNSMDFT 1119
                                             .|.|...:  ||..::|:.....:::.:....
plant   333 FEGERIEGSSKGKPKSINQCGKYERENMKNGGKSAEGPLPISVFLVASVLKDKSSKLMTEARGLD 397

  Fly  1120 DVIKFFNEMAERHNAQSVLQLARSL 1144
            ||:|..|::....:|:.....|..|
plant   398 DVVKILNDITGNLDAKKACTGAMKL 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbc	NP_001285494.1	RUN	45..218	CDD:280855
		PH_RUTBC	292..466	CDD:275431
		TBC	923..1087	CDD:214540	54/169 (32%)
AT5G54780	NP_200289.2	TBC	148..317	CDD:214540	59/275 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810