DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbc and AT4G27100

DIOPT Version :9

Sequence 1:	NP_001285494.1	Gene:	tbc / 318059	FlyBaseID:	FBgn0052506	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	NP_194440.2	Gene:	AT4G27100 / 828818	AraportID:	AT4G27100	Length:	436	Species:	Arabidopsis thaliana

Alignment Length:	264	Identity:	71/264 - (26%)
Similarity:	121/264 - (45%)	Gaps:	64/264 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   925 SSNGGVYSSEL---------LEQFGLNLHRIEKDVQRCDRN-YWYFANENLDKLRNVISTYVWEH 979
            :|||.|:..||         :.|:.|.||:|..||.|.||. .:|...|||.||.:::|.|.|..
plant   146 NSNGSVFFKELTSRGPLDKKIIQWLLTLHQIGLDVNRTDRALVFYEKKENLSKLWDILSVYAWID 210

  Fly   980 LDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMIENFPSGG---AMDMHFANMRSLIQILD 1041
            .||||.|||.||.:|::::.:||:.::.||.:||.|:..||.|.|   .::....::.|:.|::|
plant   211 NDVGYCQGMSDLCSPMIILLEDEADAFWCFERLMRRLRGNFRSTGRSVGVEAQLTHLSSITQVVD 275

  Fly  1042 SEMYDLMD--SNGDYTHFYFCYRWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFV-------- 1096
            .:::..:|  ..|||   .|..|..::.|:||..:.|....||::||.::.....:|
plant   276 PKLHQHLDKLGGGDY---LFAIRMLMVQFRREFSFCDSLYLWEMMWALEYDPDLFYVYEAHQCGN 337

  Fly  1097 --------------------------------------LFLALALLETYRDIILSNSMDFTDVIK 1123
                                                  :||..::|:.....:::.:....||:|
plant   338 EKTEGLKGKPKSIKQCGKYERQNMRNGGKSAEGPLPISVFLVASVLKDKSYKLMTEARGLDDVVK 402

  Fly  1124 FFNE 1127
            ..|:
plant   403 ILND 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbc	NP_001285494.1	RUN	45..218	CDD:280855
		PH_RUTBC	292..466	CDD:275431
		TBC	923..1087	CDD:214540	62/176 (35%)
AT4G27100	NP_194440.2	RabGAP-TBC	174..330	CDD:278964	54/158 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810