DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tbc and AT3G59570

DIOPT Version :9

Sequence 1:	NP_001285494.1	Gene:	tbc / 318059	FlyBaseID:	FBgn0052506	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	NP_001325779.1	Gene:	AT3G59570 / 825126	AraportID:	AT3G59570	Length:	744	Species:	Arabidopsis thaliana

Alignment Length:	541	Identity:	129/541 - (23%)
Similarity:	216/541 - (39%)	Gaps:	123/541 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   589 LTKERWQ-LLNVNGVLENATEFYRLVYFGGVQPELRQEVWPYLLGHYAFGSTTEDRKKQDETCKH 652
            |..|:|| |.:.:|.:.:..:..:|:..||:.|.:|.|||.:|||.||..||:|
plant    50 LKPEKWQALFDGDGKVSSFHKALKLIILGGIDPSIRAEVWEFLLGCYALSSTSE----------- 103

  Fly   653 YYETTMSEWLAVDAIVQQREK-EKTARAVAKLSSGSNSGN-DRTVRAADLEAGGDLENEVFEDIS 715
             |.|.:.        |.:||: .:..:....:.|...:|: ...|.:..::.....:|||.::..
plant   104 -YRTQLR--------VARRERYNELLKQCQMMHSTVGTGSLAYVVGSKVMDMRKSYKNEVVKEDI 159

  Fly   716 DISDPGDLEFDEQQQQQQQQAECAVSGNHLTVKPIPRAMKTSTDSGHVDESFNELDEPDEEDNKQ 780
            |.|....|:..|........     |.|.....|:.|       ||...||. :|..|
plant   160 DESREACLDGHENTDNHGDW-----SNNDTEKSPVRR-------SGSSSESV-DLVSP------- 204

  Fly   781 KQQQDEKISESESKLPDYRKLEEQINQEPSCSASTASSYETVGPG----EVHQRPNSDTRSVLSP 841
                |..|.|:.|.:|            ||      |.|....||    ::...|:.....:...
plant   205 ----DSTIYETSSFVP------------PS------SPYGFPSPGPFADDIFDFPSLPVTDLFGR 247

  Fly   842 EYLSADDLQLPDDEDAVRPPPPPAAAAVIITKASVDITNWERSPKAAEGDQMSPLE-EQAGESGG 905
            ..|....|..||:|                |....|:.:.:....:...|:.:.|. |..|.|..
plant   248 SSLGKKGLSTPDEE----------------TSTQSDLRSEDERMHSFRIDKNADLVIEPHGSSYN 296

  Fly   906 ---AGVN-----------------------MDALQ---QPKSACASPASSNGGVYSSELLEQFGL 941
               |.:|                       :|.|:   .|::..|....:.||....:.:.::..
plant   297 DVTASINSEIEVVHLQSVEKLSHSVCTSEIVDGLRISDVPETPSARETHTRGGTVKEDRVSEWLW 361

  Fly   942 NLHRIEKDVQRCDRNYWYFANE-NLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLS 1005
            .||||..||.|.|.:..::.:. ||.::.::::.|.|.....||.|||.|||:|.:.:|:|.:.:
plant   362 TLHRIVVDVVRTDSHLEFYEDPGNLGRMSDILAVYAWVDPATGYCQGMSDLVSPFVFLFEDNADA 426

  Fly  1006 YSCFCKLMERMIENF----PSGGAMDMHFANMRSLIQILDSEMYDLMDSNGDYTHFYFCYRWFLL 1066
            :.||..|:.|...||    |: |.|| ...::..::|:.|.||:..:...|..: .:|.:|..|:
plant   427 FWCFEMLIRRTRANFQMEGPT-GVMD-QLQSLWRILQLTDKEMFSHLSRIGAES-LHFAFRMLLV 488

  Fly  1067 DFKRELVYDDVFATWEVIWAA 1087
            .|:|||.::.....||::|||
plant   489 LFRRELSFNKALRMWEMMWAA 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbc	NP_001285494.1	RUN	45..218	CDD:280855
		PH_RUTBC	292..466	CDD:275431
		TBC	923..1087	CDD:214540	50/168 (30%)
AT3G59570	NP_001325779.1	TBC	<362..512	CDD:214540	50/151 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810