DRSC/TRiP Functional Genomics Resources

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Protein Alignment tbc and Tbc1d15

DIOPT Version :10

Sequence 1:NP_608395.6 Gene:tbc / 318059 FlyBaseID:FBgn0052506 Length:1155 Species:Drosophila melanogaster
Sequence 2:NP_001414153.1 Gene:Tbc1d15 / 66687 MGIID:1913937 Length:688 Species:Mus musculus


Alignment Length:461 Identity:110/461 - (23%)
Similarity:193/461 - (41%) Gaps:101/461 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   752 RAMKTSTDSGHVDESF-NELDEPDEEDNKQKQQQDEKISESESKLPDYRKL------EEQINQEP 809
            |.:..:..:..:.:|| |.||||             .....::.|.|.|||      ..:|.::|
Mouse   191 RTLLVNCQNKSLSQSFENLLDEP-------------AYGLIQAGLLDRRKLLWAIHHWRKIKKDP 242

  Fly   810 SCSASTASS------YETVGPGE--VHQRPNSDTRSVLSPEYLSADDLQLPDDED---------- 856
            ..:.....|      ::::...:  .||||.|:....||.   :...|::...|:          
Mouse   243 YTATMVGFSKVTNYIFDSLRGSDPSTHQRPPSEMADFLSD---AIPGLKINQQEEPGFEVITRID 304

  Fly   857 -AVRPPPPPAAAAVIITKASVDITNWERS--------------PKAAEGDQMSPLEEQAGESGGA 906
             ..||        |:..:..|.:..|.:|              .|...|.....|.:||.:....
Mouse   305 LGERP--------VVQRREPVSLEEWNKSLDPEGRLVAVESMKQKIFRGGLSHSLRKQAWKFLLG 361

  Fly   907 GVNMDALQQPKSACASPASSNGGVYSSELLEQFGLNLH--------------------RIEKDVQ 951
            ....|:.::.::......:.          |.|.:.|.                    .|||||.
Mouse   362 YFPWDSTKEERTQLQKQKTD----------EYFRMKLQWKSVSEAQEKRNSRLRDYRSLIEKDVN 416

  Fly   952 RCDR-NYWYFANEN--LDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLM 1013
            |.|| |.:|...:|  |..|.:::.||.....|:||:|||.||::|||.:.::|..::.||...|
Mouse   417 RTDRTNKFYEGQDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYM 481

  Fly  1014 ERMIENFPSG-GAMDMHFANMRSLIQILDSEMYDLMDSNGDYTHFYFCYRWFLLDFKRELVYDDV 1077
            ::|.:||... ..|......:.:|:::|||.....::|. |..:.|||:||.|:.||||..:.|:
Mouse   482 DQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQ-DSGYLYFCFRWLLIRFKREFSFLDI 545

  Fly  1078 FATWEVIWAAKHIASGHFVLFLALALLETYRDIILSNSMDFTDVIKFFNEMAERHNAQSVLQLAR 1142
            ...|||:|.  .:...:|.|.|..|:||:.:..|::....|.:::|..||::.:.:.:.:|..|.
Mouse   546 LRLWEVMWT--ELPCKNFHLLLCCAILESEKQQIMAKHYGFNEILKHINELSMKIDVEDILCKAE 608

  Fly  1143 SLVLQL 1148
            ::.||:
Mouse   609 AISLQM 614

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tbcNP_608395.6 RUN_SGSM1_like 21..214 CDD:439049
PH_RUTBC 292..466 CDD:275431
TBC 923..1087 CDD:214540 58/187 (31%)
Tbc1d15NP_001414153.1 PH_RBD 10..211 CDD:432305 4/19 (21%)
TBC 343..578 CDD:214540 69/247 (28%)
Blue background indicates that the domain is not in the aligned region.

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