DRSC/TRiP Functional Genomics Resources

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Protein Alignment tbc and Tbc1d15

DIOPT Version :9

Sequence 1:NP_001285494.1 Gene:tbc / 318059 FlyBaseID:FBgn0052506 Length:1155 Species:Drosophila melanogaster
Sequence 2:XP_006514020.1 Gene:Tbc1d15 / 66687 MGIID:1913937 Length:688 Species:Mus musculus


Alignment Length:461 Identity:110/461 - (23%)
Similarity:193/461 - (41%) Gaps:101/461 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   752 RAMKTSTDSGHVDESF-NELDEPDEEDNKQKQQQDEKISESESKLPDYRKL------EEQINQEP 809
            |.:..:..:..:.:|| |.||||             .....::.|.|.|||      ..:|.::|
Mouse   191 RTLLVNCQNKSLSQSFENLLDEP-------------AYGLIQAGLLDRRKLLWAIHHWRKIKKDP 242

  Fly   810 SCSASTASS------YETVGPGE--VHQRPNSDTRSVLSPEYLSADDLQLPDDED---------- 856
            ..:.....|      ::::...:  .||||.|:....||.   :...|::...|:          
Mouse   243 YTATMVGFSKVTNYIFDSLRGSDPSTHQRPPSEMADFLSD---AIPGLKINQQEEPGFEVITRID 304

  Fly   857 -AVRPPPPPAAAAVIITKASVDITNWERS--------------PKAAEGDQMSPLEEQAGESGGA 906
             ..||        |:..:..|.:..|.:|              .|...|.....|.:||.:....
Mouse   305 LGERP--------VVQRREPVSLEEWNKSLDPEGRLVAVESMKQKIFRGGLSHSLRKQAWKFLLG 361

  Fly   907 GVNMDALQQPKSACASPASSNGGVYSSELLEQFGLNLH--------------------RIEKDVQ 951
            ....|:.::.::......:.          |.|.:.|.                    .|||||.
Mouse   362 YFPWDSTKEERTQLQKQKTD----------EYFRMKLQWKSVSEAQEKRNSRLRDYRSLIEKDVN 416

  Fly   952 RCDR-NYWYFANEN--LDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLM 1013
            |.|| |.:|...:|  |..|.:::.||.....|:||:|||.||::|||.:.::|..::.||...|
Mouse   417 RTDRTNKFYEGQDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYM 481

  Fly  1014 ERMIENFPSG-GAMDMHFANMRSLIQILDSEMYDLMDSNGDYTHFYFCYRWFLLDFKRELVYDDV 1077
            ::|.:||... ..|......:.:|:::|||.....::|. |..:.|||:||.|:.||||..:.|:
Mouse   482 DQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQ-DSGYLYFCFRWLLIRFKREFSFLDI 545

  Fly  1078 FATWEVIWAAKHIASGHFVLFLALALLETYRDIILSNSMDFTDVIKFFNEMAERHNAQSVLQLAR 1142
            ...|||:|.  .:...:|.|.|..|:||:.:..|::....|.:::|..||::.:.:.:.:|..|.
Mouse   546 LRLWEVMWT--ELPCKNFHLLLCCAILESEKQQIMAKHYGFNEILKHINELSMKIDVEDILCKAE 608

  Fly  1143 SLVLQL 1148
            ::.||:
Mouse   609 AISLQM 614

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tbcNP_001285494.1 RUN 45..218 CDD:280855
PH_RUTBC 292..466 CDD:275431
TBC 923..1087 CDD:214540 58/187 (31%)
Tbc1d15XP_006514020.1 DUF3548 10..211 CDD:371881 4/19 (21%)
TBC 343..578 CDD:214540 69/247 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5210
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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